Seruca R - Search Results

1

Targeting the PI3K Signalling as a Therapeutic Strategy in Colorectal Cancer.

Fernandes MS, Sanches JM, Seruca R. Fernandes MS, et al. Among authors: seruca r. Adv Exp Med Biol. 2018;1110:35-53. doi: 10.1007/978-3-030-02771-1_4. Adv Exp Med Biol. 2018. PMID: 30623365 Review.

2

Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer.

Oliveira C, Velho S, Domingo E, Preto A, Hofstra RM, Hamelin R, Yamamoto H, Seruca R, Schwartz S Jr. Oliveira C, et al. Among authors: seruca r. Oncogene. 2005 Nov 17;24(51):7630-4. doi: 10.1038/sj.onc.1208906. Oncogene. 2005. PMID: 16007118

3

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression.

Oliveira C, Velho S, Moutinho C, Ferreira A, Preto A, Domingo E, Capelinha AF, Duval A, Hamelin R, Machado JC, Schwartz S Jr, Carneiro F, Seruca R. Oliveira C, et al. Among authors: seruca r. Oncogene. 2007 Jan 4;26(1):158-63. doi: 10.1038/sj.onc.1209758. Epub 2006 Sep 4. Oncogene. 2007. PMID: 16953233

4

A subset of colorectal carcinomas express c-KIT protein independently of BRAF and/or KRAS activation.

Preto A, Moutinho C, Velho S, Oliveira C, Rebocho AP, Figueiredo J, Soares P, Lopes JM, Seruca R. Preto A, et al. Among authors: seruca r. Virchows Arch. 2007 Jun;450(6):619-26. doi: 10.1007/s00428-007-0420-9. Epub 2007 May 9. Virchows Arch. 2007. PMID: 17487504

5

BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations.

Preto A, Figueiredo J, Velho S, Ribeiro AS, Soares P, Oliveira C, Seruca R. Preto A, et al. Among authors: seruca r. J Pathol. 2008 Feb;214(3):320-7. doi: 10.1002/path.2295. J Pathol. 2008. PMID: 18098337

6

BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?

Velho S, Moutinho C, Cirnes L, Albuquerque C, Hamelin R, Schmitt F, Carneiro F, Oliveira C, Seruca R. Velho S, et al. Among authors: seruca r. BMC Cancer. 2008 Sep 9;8:255. doi: 10.1186/1471-2407-8-255. BMC Cancer. 2008. PMID: 18782444 Free PMC article.

7

Proliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations.

Preto A, Gonçalves J, Rebocho AP, Figueiredo J, Meireles AM, Rocha AS, Vasconcelos HM, Seca H, Seruca R, Soares P, Sobrinho-Simões M. Preto A, et al. Among authors: seruca r. BMC Cancer. 2009 Oct 31;9:387. doi: 10.1186/1471-2407-9-387. BMC Cancer. 2009. PMID: 19878585 Free PMC article.

8

Oncogenic mutations in gastric cancer with microsatellite instability.

Corso G, Velho S, Paredes J, Pedrazzani C, Martins D, Milanezi F, Pascale V, Vindigni C, Pinheiro H, Leite M, Marrelli D, Sousa S, Carneiro F, Oliveira C, Roviello F, Seruca R. Corso G, et al. Among authors: seruca r. Eur J Cancer. 2011 Feb;47(3):443-51. doi: 10.1016/j.ejca.2010.09.008. Eur J Cancer. 2011. PMID: 20937558

9

KRAS signaling pathway alterations in microsatellite unstable gastrointestinal cancers.

Velho S, Corso G, Oliveíra C, Seruca R. Velho S, et al. Among authors: seruca r. Adv Cancer Res. 2010;109:123-43. doi: 10.1016/B978-0-12-380890-5.00004-1. Adv Cancer Res. 2010. PMID: 21070916 Review.

10

Epithelial E- and P-cadherins: role and clinical significance in cancer.

Paredes J, Figueiredo J, Albergaria A, Oliveira P, Carvalho J, Ribeiro AS, Caldeira J, Costa AM, Simões-Correia J, Oliveira MJ, Pinheiro H, Pinho SS, Mateus R, Reis CA, Leite M, Fernandes MS, Schmitt F, Carneiro F, Figueiredo C, Oliveira C, Seruca R. Paredes J, et al. Among authors: seruca r. Biochim Biophys Acta. 2012 Dec;1826(2):297-311. doi: 10.1016/j.bbcan.2012.05.002. Epub 2012 May 19. Biochim Biophys Acta. 2012. PMID: 22613680 Review.

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