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PI3Kδ inhibition reshapes follicular lymphoma-immune microenvironment cross talk and unleashes the activity of venetoclax.
Serrat N, Guerrero-Hernández M, Matas-Céspedes A, Yahiaoui A, Valero JG, Nadeu F, Clot G, Di Re M, Corbera-Bellalta M, Magnano L, Rivas-Delgado A, Enjuanes A, Beà S, Cid MC, Campo E, Montero J, Hodson DJ, López-Guillermo A, Colomer D, Tannheimer S, Pérez-Galán P. Serrat N, et al. Blood Adv. 2020 Sep 8;4(17):4217-4231. doi: 10.1182/bloodadvances.2020001584. Blood Adv. 2020. PMID: 32898249 Free PMC article.
The receptor of the colony-stimulating factor-1 (CSF-1R) is a novel prognostic factor and therapeutic target in follicular lymphoma.
Valero JG, Matas-Céspedes A, Arenas F, Rodriguez V, Carreras J, Serrat N, Guerrero-Hernández M, Yahiaoui A, Balagué O, Martin S, Capdevila C, Hernández L, Magnano L, Rivas-Delgado A, Tannheimer S, Cid MC, Campo E, López-Guillermo A, Colomer D, Pérez-Galán P. Valero JG, et al. Among authors: serrat n. Leukemia. 2021 Sep;35(9):2635-2649. doi: 10.1038/s41375-021-01201-9. Epub 2021 Mar 17. Leukemia. 2021. PMID: 33731849 Free PMC article.
Daratumumab displays in vitro and in vivo anti-tumor activity in models of B-cell non-Hodgkin lymphoma and improves responses to standard chemo-immunotherapy regimens.
Vidal-Crespo A, Matas-Céspedes A, Rodriguez V, Rossi C, Valero JG, Serrat N, Sanjuan-Pla A, Menéndez P, Roué G, López-Guillermo A, Giné E, Campo E, Colomer D, Bezombes C, van Bueren JL, Chiu C, Doshi P, Pérez-Galán P. Vidal-Crespo A, et al. Among authors: serrat n. Haematologica. 2020 Apr;105(4):1032-1041. doi: 10.3324/haematol.2018.211904. Epub 2019 Jul 11. Haematologica. 2020. PMID: 31296574 Free PMC article.
Cell death, it always matters.
Comalada M, Serrat N, Xaus J. Comalada M, et al. Among authors: serrat n. J Leukoc Biol. 2010 Dec;88(6):1063-4; author reply 1065-6. doi: 10.1189/jlb.0710401. J Leukoc Biol. 2010. PMID: 21123293 No abstract available.
24 results