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Anti-leishmanial effect of spiro dihydroquinoline-oxindoles on volume regulation decrease and sterol biosynthesis of Leishmania braziliensis.
Leañez J, Nuñez J, García-Marchan Y, Sojo F, Arvelo F, Rodriguez D, Buscema I, Alvarez-Aular A, Bello Forero JS, Kouznetsov VV, Serrano-Martín X. Leañez J, et al. Among authors: serrano martin x. Exp Parasitol. 2019 Mar;198:31-38. doi: 10.1016/j.exppara.2019.01.011. Epub 2019 Jan 25. Exp Parasitol. 2019. PMID: 30690024
Anti-leishmanial evaluation of C2-aryl quinolines: mechanistic insight on bioenergetics and sterol biosynthetic pathway of Leishmania braziliensis.
Bompart D, Núñez-Durán J, Rodríguez D, Kouznetsov VV, Meléndez Gómez CM, Sojo F, Arvelo F, Visbal G, Alvarez A, Serrano-Martín X, García-Marchán Y. Bompart D, et al. Among authors: serrano martin x. Bioorg Med Chem. 2013 Jul 15;21(14):4426-31. doi: 10.1016/j.bmc.2013.04.063. Epub 2013 May 9. Bioorg Med Chem. 2013. PMID: 23719286
Design, synthesis, structure-activity relationship and mechanism of action studies of a series of 4-chloro-1-phthalazinyl hydrazones as a potent agent against Leishmania braziliensis.
Romero AH, Medina R, Alcala A, García-Marchan Y, Núñez-Duran J, Leañez J, Mijoba A, Ciangherotti C, Serrano-Martín X, López SE. Romero AH, et al. Among authors: serrano martin x. Eur J Med Chem. 2017 Feb 15;127:606-620. doi: 10.1016/j.ejmech.2017.01.022. Epub 2017 Jan 17. Eur J Med Chem. 2017. PMID: 28119201
Mechanism of Action of Miltefosine on Leishmania donovani Involves the Impairment of Acidocalcisome Function and the Activation of the Sphingosine-Dependent Plasma Membrane Ca2+ Channel.
Pinto-Martinez AK, Rodriguez-Durán J, Serrano-Martin X, Hernandez-Rodriguez V, Benaim G. Pinto-Martinez AK, et al. Among authors: serrano martin x. Antimicrob Agents Chemother. 2017 Dec 21;62(1):e01614-17. doi: 10.1128/AAC.01614-17. Print 2018 Jan. Antimicrob Agents Chemother. 2017. PMID: 29061745 Free PMC article.