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Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity.
EMBO J. 2023 Sep 18;42(18):e113190. doi: 10.15252/embj.2022113190. Epub 2023 Jul 26.
EMBO J. 2023.
PMID: 37492888
Free PMC article.
RAD54L2 counters TOP2-DNA adducts to promote genome stability.
D'Alessandro G, Morales-Juarez DA, Richards SL, Nitiss KC, Serrano-Benitez A, Wang J, Thomas JC, Gupta V, Voigt A, Belotserkovskaya R, Goh CG, Bowden AR, Galanty Y, Beli P, Nitiss JL, Zagnoli-Vieira G, Jackson SP.
D'Alessandro G, et al. Among authors: serrano benitez a.
Sci Adv. 2023 Dec 8;9(49):eadl2108. doi: 10.1126/sciadv.adl2108. Epub 2023 Dec 6.
Sci Adv. 2023.
PMID: 38055822
Free PMC article.
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Revolutionizing DNA repair research and cancer therapy with CRISPR-Cas screens.
Awwad SW, Serrano-Benitez A, Thomas JC, Gupta V, Jackson SP.
Awwad SW, et al. Among authors: serrano benitez a.
Nat Rev Mol Cell Biol. 2023 Jul;24(7):477-494. doi: 10.1038/s41580-022-00571-x. Epub 2023 Feb 13.
Nat Rev Mol Cell Biol. 2023.
PMID: 36781955
Review.
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A Genetic Map of the Response to DNA Damage in Human Cells.
Olivieri M, Cho T, Álvarez-Quilón A, Li K, Schellenberg MJ, Zimmermann M, Hustedt N, Rossi SE, Adam S, Melo H, Heijink AM, Sastre-Moreno G, Moatti N, Szilard RK, McEwan A, Ling AK, Serrano-Benitez A, Ubhi T, Feng S, Pawling J, Delgado-Sainz I, Ferguson MW, Dennis JW, Brown GW, Cortés-Ledesma F, Williams RS, Martin A, Xu D, Durocher D.
Olivieri M, et al. Among authors: serrano benitez a.
Cell. 2020 Jul 23;182(2):481-496.e21. doi: 10.1016/j.cell.2020.05.040. Epub 2020 Jul 9.
Cell. 2020.
PMID: 32649862
Free PMC article.
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Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency.
Álvarez-Quilón A, Terrón-Bautista J, Delgado-Sainz I, Serrano-Benítez A, Romero-Granados R, Martínez-García PM, Jimeno-González S, Bernal-Lozano C, Quintero C, García-Quintanilla L, Cortés-Ledesma F.
Álvarez-Quilón A, et al. Among authors: serrano benitez a.
Nat Commun. 2020 Feb 14;11(1):910. doi: 10.1038/s41467-020-14638-w.
Nat Commun. 2020.
PMID: 32060399
Free PMC article.
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"An End to a Means": How DNA-End Structure Shapes the Double-Strand Break Repair Process.
Serrano-Benítez A, Cortés-Ledesma F, Ruiz JF.
Serrano-Benítez A, et al.
Front Mol Biosci. 2020 Jan 10;6:153. doi: 10.3389/fmolb.2019.00153. eCollection 2019.
Front Mol Biosci. 2020.
PMID: 31998749
Free PMC article.
Review.
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GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells.
Pintado-Berninches L, Fernandez-Varas B, Benitez-Buelga C, Manguan-Garcia C, Serrano-Benitez A, Iarriccio L, Carrillo J, Guenechea G, Egusquiaguirre SP, Pedraz JL, Hernández RM, Igartua M, Arias-Salgado EG, Cortés-Ledesma F, Sastre L, Perona R.
Pintado-Berninches L, et al. Among authors: serrano benitez a.
Cell Death Differ. 2019 Oct;26(10):1998-2014. doi: 10.1038/s41418-018-0272-7. Epub 2019 Jan 22.
Cell Death Differ. 2019.
PMID: 30670828
Free PMC article.
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ATM specifically mediates repair of double-strand breaks with blocked DNA ends.
Álvarez-Quilón A, Serrano-Benítez A, Lieberman JA, Quintero C, Sánchez-Gutiérrez D, Escudero LM, Cortés-Ledesma F.
Álvarez-Quilón A, et al. Among authors: serrano benitez a.
Nat Commun. 2014 Feb 27;5:3347. doi: 10.1038/ncomms4347.
Nat Commun. 2014.
PMID: 24572510
Free PMC article.
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