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Page 1
A Genetic Map of the Response to DNA Damage in Human Cells.
Olivieri M, Cho T, Álvarez-Quilón A, Li K, Schellenberg MJ, Zimmermann M, Hustedt N, Rossi SE, Adam S, Melo H, Heijink AM, Sastre-Moreno G, Moatti N, Szilard RK, McEwan A, Ling AK, Serrano-Benitez A, Ubhi T, Feng S, Pawling J, Delgado-Sainz I, Ferguson MW, Dennis JW, Brown GW, Cortés-Ledesma F, Williams RS, Martin A, Xu D, Durocher D. Olivieri M, et al. Among authors: serrano benitez a. Cell. 2020 Jul 23;182(2):481-496.e21. doi: 10.1016/j.cell.2020.05.040. Epub 2020 Jul 9. Cell. 2020. PMID: 32649862 Free PMC article.
ATM specifically mediates repair of double-strand breaks with blocked DNA ends.
Álvarez-Quilón A, Serrano-Benítez A, Lieberman JA, Quintero C, Sánchez-Gutiérrez D, Escudero LM, Cortés-Ledesma F. Álvarez-Quilón A, et al. Among authors: serrano benitez a. Nat Commun. 2014 Feb 27;5:3347. doi: 10.1038/ncomms4347. Nat Commun. 2014. PMID: 24572510 Free PMC article.
Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency.
Álvarez-Quilón A, Terrón-Bautista J, Delgado-Sainz I, Serrano-Benítez A, Romero-Granados R, Martínez-García PM, Jimeno-González S, Bernal-Lozano C, Quintero C, García-Quintanilla L, Cortés-Ledesma F. Álvarez-Quilón A, et al. Among authors: serrano benitez a. Nat Commun. 2020 Feb 14;11(1):910. doi: 10.1038/s41467-020-14638-w. Nat Commun. 2020. PMID: 32060399 Free PMC article.
GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells.
Pintado-Berninches L, Fernandez-Varas B, Benitez-Buelga C, Manguan-Garcia C, Serrano-Benitez A, Iarriccio L, Carrillo J, Guenechea G, Egusquiaguirre SP, Pedraz JL, Hernández RM, Igartua M, Arias-Salgado EG, Cortés-Ledesma F, Sastre L, Perona R. Pintado-Berninches L, et al. Among authors: serrano benitez a. Cell Death Differ. 2019 Oct;26(10):1998-2014. doi: 10.1038/s41418-018-0272-7. Epub 2019 Jan 22. Cell Death Differ. 2019. PMID: 30670828 Free PMC article.
RAD54L2 counters TOP2-DNA adducts to promote genome stability.
D'Alessandro G, Morales-Juarez DA, Richards SL, Nitiss KC, Serrano-Benitez A, Wang J, Thomas JC, Gupta V, Voigt A, Belotserkovskaya R, Goh CG, Bowden AR, Galanty Y, Beli P, Nitiss JL, Zagnoli-Vieira G, Jackson SP. D'Alessandro G, et al. Among authors: serrano benitez a. Sci Adv. 2023 Dec 8;9(49):eadl2108. doi: 10.1126/sciadv.adl2108. Epub 2023 Dec 6. Sci Adv. 2023. PMID: 38055822 Free PMC article.
Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity.
Serrano-Benitez A, Wells SE, Drummond-Clarke L, Russo LC, Thomas JC, Leal GA, Farrow M, Edgerton JM, Balasubramanian S, Yang M, Frezza C, Gautam A, Brazina J, Burdova K, Hoch NC, Jackson SP, Caldecott KW. Serrano-Benitez A, et al. EMBO J. 2023 Sep 18;42(18):e113190. doi: 10.15252/embj.2022113190. Epub 2023 Jul 26. EMBO J. 2023. PMID: 37492888 Free PMC article.