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SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway.
Santos-Barriopedro I, Bosch-Presegué L, Marazuela-Duque A, de la Torre C, Colomer C, Vazquez BN, Fuhrmann T, Martínez-Pastor B, Lu W, Braun T, Bober E, Jenuwein T, Serrano L, Esteller M, Chen Z, Barceló-Batllori S, Mostoslavsky R, Espinosa L, Vaquero A. Santos-Barriopedro I, et al. Among authors: serrano l. Nat Commun. 2018 Jan 9;9(1):101. doi: 10.1038/s41467-017-02586-x. Nat Commun. 2018. PMID: 29317652 Free PMC article.
The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation.
Serrano L, Martínez-Redondo P, Marazuela-Duque A, Vazquez BN, Dooley SJ, Voigt P, Beck DB, Kane-Goldsmith N, Tong Q, Rabanal RM, Fondevila D, Muñoz P, Krüger M, Tischfield JA, Vaquero A. Serrano L, et al. Genes Dev. 2013 Mar 15;27(6):639-53. doi: 10.1101/gad.211342.112. Epub 2013 Mar 6. Genes Dev. 2013. PMID: 23468428 Free PMC article.
Chromatin structure, pluripotency and differentiation.
Serrano L, Vazquez BN, Tischfield J. Serrano L, et al. Exp Biol Med (Maywood). 2013 Mar;238(3):259-70. doi: 10.1177/1535370213480718. Exp Biol Med (Maywood). 2013. PMID: 23598971 Review.
SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair.
Vazquez BN, Thackray JK, Simonet NG, Kane-Goldsmith N, Martinez-Redondo P, Nguyen T, Bunting S, Vaquero A, Tischfield JA, Serrano L. Vazquez BN, et al. Among authors: serrano l. EMBO J. 2016 Jul 15;35(14):1488-503. doi: 10.15252/embj.201593499. Epub 2016 May 24. EMBO J. 2016. PMID: 27225932 Free PMC article.
Sirtuins and DNA damage repair: SIRT7 comes to play.
Vazquez BN, Thackray JK, Serrano L. Vazquez BN, et al. Among authors: serrano l. Nucleus. 2017 Mar 4;8(2):107-115. doi: 10.1080/19491034.2016.1264552. Epub 2017 Feb 17. Nucleus. 2017. PMID: 28406750 Free PMC article. Review.
Mammalian HP1 Isoforms Have Specific Roles in Heterochromatin Structure and Organization.
Bosch-Presegué L, Raurell-Vila H, Thackray JK, González J, Casal C, Kane-Goldsmith N, Vizoso M, Brown JP, Gómez A, Ausió J, Zimmermann T, Esteller M, Schotta G, Singh PB, Serrano L, Vaquero A. Bosch-Presegué L, et al. Among authors: serrano l. Cell Rep. 2017 Nov 21;21(8):2048-2057. doi: 10.1016/j.celrep.2017.10.092. Cell Rep. 2017. PMID: 29166597 Free article.
906 results