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Low input capture Hi-C (liCHi-C) identifies promoter-enhancer interactions at high-resolution.
Tomás-Daza L, Rovirosa L, López-Martí P, Nieto-Aliseda A, Serra F, Planas-Riverola A, Molina O, McDonald R, Ghevaert C, Cuatrecasas E, Costa D, Camós M, Bueno C, Menéndez P, Valencia A, Javierre BM. Tomás-Daza L, et al. Among authors: serra f. Nat Commun. 2023 Jan 17;14(1):268. doi: 10.1038/s41467-023-35911-8. Nat Commun. 2023. PMID: 36650138 Free PMC article.
p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response.
Serra F, Nieto-Aliseda A, Fanlo-Escudero L, Rovirosa L, Cabrera-Pasadas M, Lazarenkov A, Urmeneta B, Alcalde-Merino A, Nola EM, Okorokov AL, Fraser P, Graupera M, Castillo SD, Sardina JL, Valencia A, Javierre BM. Serra F, et al. Nat Commun. 2024 Apr 1;15(1):2821. doi: 10.1038/s41467-024-46666-1. Nat Commun. 2024. PMID: 38561401 Free PMC article.
STAG2 loss-of-function affects short-range genomic contacts and modulates the basal-luminal transcriptional program of bladder cancer cells.
Richart L, Lapi E, Pancaldi V, Cuenca-Ardura M, Pau EC, Madrid-Mencía M, Neyret-Kahn H, Radvanyi F, Rodríguez JA, Cuartero Y, Serra F, Le Dily F, Valencia A, Marti-Renom MA, Real FX. Richart L, et al. Among authors: serra f. Nucleic Acids Res. 2021 Nov 8;49(19):11005-11021. doi: 10.1093/nar/gkab864. Nucleic Acids Res. 2021. PMID: 34648034 Free PMC article.
The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia.
Beekman R, Chapaprieta V, Russiñol N, Vilarrasa-Blasi R, Verdaguer-Dot N, Martens JHA, Duran-Ferrer M, Kulis M, Serra F, Javierre BM, Wingett SW, Clot G, Queirós AC, Castellano G, Blanc J, Gut M, Merkel A, Heath S, Vlasova A, Ullrich S, Palumbo E, Enjuanes A, Martín-García D, Beà S, Pinyol M, Aymerich M, Royo R, Puiggros M, Torrents D, Datta A, Lowy E, Kostadima M, Roller M, Clarke L, Flicek P, Agirre X, Prosper F, Baumann T, Delgado J, López-Guillermo A, Fraser P, Yaspo ML, Guigó R, Siebert R, Martí-Renom MA, Puente XS, López-Otín C, Gut I, Stunnenberg HG, Campo E, Martin-Subero JI. Beekman R, et al. Among authors: serra f. Nat Med. 2018 Jun;24(6):868-880. doi: 10.1038/s41591-018-0028-4. Epub 2018 May 21. Nat Med. 2018. PMID: 29785028 Free PMC article.
Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming.
Stadhouders R, Vidal E, Serra F, Di Stefano B, Le Dily F, Quilez J, Gomez A, Collombet S, Berenguer C, Cuartero Y, Hecht J, Filion GJ, Beato M, Marti-Renom MA, Graf T. Stadhouders R, et al. Among authors: serra f. Nat Genet. 2018 Feb;50(2):238-249. doi: 10.1038/s41588-017-0030-7. Epub 2018 Jan 15. Nat Genet. 2018. PMID: 29335546 Free PMC article.
Fungal metabolite 6-pentyl-α-pyrone reduces canine coronavirus infection.
Cerracchio C, Del Sorbo L, Serra F, Staropoli A, Amoroso MG, Vinale F, Fiorito F. Cerracchio C, et al. Among authors: serra f. Heliyon. 2024 Mar 20;10(6):e28351. doi: 10.1016/j.heliyon.2024.e28351. eCollection 2024 Mar 30. Heliyon. 2024. PMID: 38545179 Free PMC article.
349 results