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A hybrid open-top light-sheet microscope for versatile multi-scale imaging of cleared tissues.
Glaser AK, Bishop KW, Barner LA, Susaki EA, Kubota SI, Gao G, Serafin RB, Balaram P, Turschak E, Nicovich PR, Lai H, Lucas LAG, Yi Y, Nichols EK, Huang H, Reder NP, Wilson JJ, Sivakumar R, Shamskhou E, Stoltzfus CR, Wei X, Hempton AK, Pende M, Murawala P, Dodt HU, Imaizumi T, Shendure J, Beliveau BJ, Gerner MY, Xin L, Zhao H, True LD, Reid RC, Chandrashekar J, Ueda HR, Svoboda K, Liu JTC. Glaser AK, et al. Among authors: serafin rb. Nat Methods. 2022 May;19(5):613-619. doi: 10.1038/s41592-022-01468-5. Epub 2022 May 11. Nat Methods. 2022. PMID: 35545715 Free PMC article.
Prostate Cancer Risk Stratification via Nondestructive 3D Pathology with Deep Learning-Assisted Gland Analysis.
Xie W, Reder NP, Koyuncu C, Leo P, Hawley S, Huang H, Mao C, Postupna N, Kang S, Serafin R, Gao G, Han Q, Bishop KW, Barner LA, Fu P, Wright JL, Keene CD, Vaughan JC, Janowczyk A, Glaser AK, Madabhushi A, True LD, Liu JTC. Xie W, et al. Cancer Res. 2022 Jan 15;82(2):334-345. doi: 10.1158/0008-5472.CAN-21-2843. Epub 2021 Dec 1. Cancer Res. 2022. PMID: 34853071 Free PMC article.
An end-to-end workflow for non-destructive 3D pathology.
Bishop KW, Barner LAE, Han Q, Baraznenok E, Lan L, Poudel C, Gao G, Serafin RB, Chow SSL, Glaser AK, Janowczyk A, Brenes D, Huang H, Miyasato D, True LD, Kang S, Vaughan JC, Liu JTC. Bishop KW, et al. Among authors: serafin rb. bioRxiv [Preprint]. 2023 Aug 6:2023.08.03.551845. doi: 10.1101/2023.08.03.551845. bioRxiv. 2023. PMID: 37577615 Free PMC article. Updated. Preprint.
Visual Assessment of 2-Dimensional Levels Within 3-Dimensional Pathology Data Sets of Prostate Needle Biopsies Reveals Substantial Spatial Heterogeneity.
Koyuncu C, Janowczyk A, Farre X, Pathak T, Mirtti T, Fernandez PL, Pons L, Reder NP, Serafin R, Chow SSL, Viswanathan VS, Glaser AK, True LD, Liu JTC, Madabhushi A. Koyuncu C, et al. Lab Invest. 2023 Dec;103(12):100265. doi: 10.1016/j.labinv.2023.100265. Epub 2023 Oct 18. Lab Invest. 2023. PMID: 37858679 Free PMC article.
An end-to-end workflow for nondestructive 3D pathology.
Bishop KW, Erion Barner LA, Han Q, Baraznenok E, Lan L, Poudel C, Gao G, Serafin RB, Chow SSL, Glaser AK, Janowczyk A, Brenes D, Huang H, Miyasato D, True LD, Kang S, Vaughan JC, Liu JTC. Bishop KW, et al. Among authors: serafin rb. Nat Protoc. 2024 Apr;19(4):1122-1148. doi: 10.1038/s41596-023-00934-4. Epub 2024 Jan 23. Nat Protoc. 2024. PMID: 38263522 Review.
Direct three-dimensional segmentation of prostate glands with nnU-Net.
Wang R, Chow SSL, Serafin RB, Xie W, Han Q, Baraznenok E, Lan L, Bishop KW, Liu JTC. Wang R, et al. Among authors: serafin rb. J Biomed Opt. 2024 Mar;29(3):036001. doi: 10.1117/1.JBO.29.3.036001. Epub 2024 Mar 1. J Biomed Opt. 2024. PMID: 38434772 Free PMC article.
Analysis of 3D pathology samples using weakly supervised AI.
Song AH, Williams M, Williamson DFK, Chow SSL, Jaume G, Gao G, Zhang A, Chen B, Baras AS, Serafin R, Colling R, Downes MR, Farré X, Humphrey P, Verrill C, True LD, Parwani AV, Liu JTC, Mahmood F. Song AH, et al. Cell. 2024 May 9;187(10):2502-2520.e17. doi: 10.1016/j.cell.2024.03.035. Cell. 2024. PMID: 38729110
13 results