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Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species.
González-Lizárraga F, Socías SB, Ávila CL, Torres-Bugeau CM, Barbosa LR, Binolfi A, Sepúlveda-Díaz JE, Del-Bel E, Fernandez CO, Papy-Garcia D, Itri R, Raisman-Vozari R, Chehín RN. González-Lizárraga F, et al. Among authors: sepulveda diaz je. Sci Rep. 2017 Feb 3;7:41755. doi: 10.1038/srep41755. Sci Rep. 2017. PMID: 28155912 Free PMC article.
Glycosaminoglycans, protein aggregation and neurodegeneration.
Papy-Garcia D, Christophe M, Huynh MB, Fernando S, Ludmilla S, Sepulveda-Diaz JE, Raisman-Vozari R. Papy-Garcia D, et al. Curr Protein Pept Sci. 2011 May;12(3):258-68. doi: 10.2174/138920311795860188. Curr Protein Pept Sci. 2011. PMID: 21348835 Review.
HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer's disease-related tau pathology.
Sepulveda-Diaz JE, Alavi Naini SM, Huynh MB, Ouidja MO, Yanicostas C, Chantepie S, Villares J, Lamari F, Jospin E, van Kuppevelt TH, Mensah-Nyagan AG, Raisman-Vozari R, Soussi-Yanicostas N, Papy-Garcia D. Sepulveda-Diaz JE, et al. Brain. 2015 May;138(Pt 5):1339-54. doi: 10.1093/brain/awv056. Epub 2015 Apr 4. Brain. 2015. PMID: 25842390 Free PMC article.
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