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Page 1
Circulating metabolome landscape in Lynch syndrome.
Jokela TA, Karppinen JE, Kärkkäinen M, Mecklin JP, Walker S, Seppälä TT, Laakkonen EK. Jokela TA, et al. Among authors: seppala tt. Cancer Metab. 2024 Feb 5;12(1):4. doi: 10.1186/s40170-024-00331-9. Cancer Metab. 2024. PMID: 38317210 Free PMC article.
Lynch Syndrome Genetics and Clinical Implications.
Peltomäki P, Nyström M, Mecklin JP, Seppälä TT. Peltomäki P, et al. Among authors: seppala tt. Gastroenterology. 2023 Apr;164(5):783-799. doi: 10.1053/j.gastro.2022.08.058. Epub 2023 Jan 24. Gastroenterology. 2023. PMID: 36706841 Free article.
The prognostic role of tumor budding and tumor-stroma ratio in pulmonary metastasis of colorectal carcinoma.
Karjula T, Kemi N, Niskakangas A, Mustonen O, Puro I, Pohjanen VM, Kuopio T, Elomaa H, Ahtiainen M, Mecklin JP, Seppälä TT, Wirta EV, Sihvo E, Väyrynen JP, Yannopoulos F, Helminen O. Karjula T, et al. Among authors: seppala tt. Eur J Surg Oncol. 2023 Jul;49(7):1298-1306. doi: 10.1016/j.ejso.2023.02.009. Epub 2023 Feb 21. Eur J Surg Oncol. 2023. PMID: 36841693 Free article.
Spatially resolved multimarker evaluation of CD274 (PD-L1)/PDCD1 (PD-1) immune checkpoint expression and macrophage polarisation in colorectal cancer.
Elomaa H, Ahtiainen M, Väyrynen SA, Ogino S, Nowak JA, Lau MC, Helminen O, Wirta EV, Seppälä TT, Böhm J, Mecklin JP, Kuopio T, Väyrynen JP. Elomaa H, et al. Among authors: seppala tt. Br J Cancer. 2023 Jun;128(11):2104-2115. doi: 10.1038/s41416-023-02238-6. Epub 2023 Mar 31. Br J Cancer. 2023. PMID: 37002343 Free PMC article.
Immunological and prognostic significance of tumour necrosis in colorectal cancer.
Kastinen M, Sirniö P, Elomaa H, Ahtiainen M, Väyrynen SA, Herzig KH, Meriläinen S, Aro R, Häivälä R, Rautio T, Saarnio J, Wirta EV, Helminen O, Seppälä TT, Kuopio T, Böhm J, Tuomisto A, Mecklin JP, Mäkinen MJ, Väyrynen JP. Kastinen M, et al. Among authors: seppala tt. Br J Cancer. 2023 Jun;128(12):2218-2226. doi: 10.1038/s41416-023-02258-2. Epub 2023 Apr 8. Br J Cancer. 2023. PMID: 37031328 Free PMC article.
Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database.
Dominguez-Valentin M, Haupt S, Seppälä TT, Sampson JR, Sunde L, Bernstein I, Jenkins MA, Engel C, Aretz S, Nielsen M, Capella G, Balaguer F, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Della Valle A, Heinimann K, Dębniak T, Fruscio R, Lopez-Koestner F, Alvarez-Valenzuela K, Katz LH, Laish I, Vainer E, Vaccaro C, Carraro DM, Monahan K, Half E, Stakelum A, Winter D, Kennelly R, Gluck N, Sheth H, Abu-Freha N, Greenblatt M, Rossi BM, Bohorquez M, Cavestro GM, Lino-Silva LS, Horisberger K, Tibiletti MG, Nascimento ID, Thomas H, Rossi NT, Apolinário da Silva L, Zaránd A, Ruiz-Bañobre J, Heuveline V, Mecklin JP, Pylvänäinen K, Renkonen-Sinisalo L, Lepistö A, Peltomäki P, Therkildsen C, Madsen MG, Burgdorf SK, Hopper JL, Win AK, Haile RW, Lindor N, Gallinger S, Le Marchand L, Newcomb PA, Figueiredo J, Buchanan DD, Thibodeau SN, von Knebel Doeberitz M, Loeffler M, Rahner N, Schröck E, Steinke-Lange V, Schmiegel W, Vangala D, Perne C, Hüneburg R, Redler S, Büttner R, Weitz J, Pineda M, Duenas N, Vidal JB, Moreira L, Sánchez A, Hovig E, Nakken S, Green K, Lalloo F, Hill J, Crosbie E, Mints M, Goldb… See abstract for full author list ➔ Dominguez-Valentin M, et al. Among authors: seppala tt. EClinicalMedicine. 2023 Mar 20;58:101909. doi: 10.1016/j.eclinm.2023.101909. eCollection 2023 Apr. EClinicalMedicine. 2023. PMID: 37181409 Free PMC article.
Tertiary lymphoid structures in pulmonary metastases of microsatellite stable colorectal cancer.
Karjula T, Niskakangas A, Mustonen O, Puro I, Elomaa H, Ahtiainen M, Kuopio T, Mecklin JP, Seppälä TT, Wirta EV, Sihvo E, Yannopoulos F, Helminen O, Väyrynen JP. Karjula T, et al. Among authors: seppala tt. Virchows Arch. 2023 Jul;483(1):21-32. doi: 10.1007/s00428-023-03577-8. Epub 2023 Jun 20. Virchows Arch. 2023. PMID: 37337034 Free PMC article.
Dominantly inherited micro-satellite instable cancer - the four Lynch syndromes - an EHTG, PLSD position statement.
Møller P, Seppälä TT, Ahadova A, Crosbie EJ, Holinski-Feder E, Scott R, Haupt S, Möslein G, Winship I, Broeke SWB, Kohut KE, Ryan N, Bauerfeind P, Thomas LE, Evans DG, Aretz S, Sijmons RH, Half E, Heinimann K, Horisberger K, Monahan K, Engel C, Cavestro GM, Fruscio R, Abu-Freha N, Zohar L, Laghi L, Bertario L, Bonanni B, Tibiletti MG, Lino-Silva LS, Vaccaro C, Valle AD, Rossi BM, da Silva LA, de Oliveira Nascimento IL, Rossi NT, Dębniak T, Mecklin JP, Bernstein I, Lindblom A, Sunde L, Nakken S, Heuveline V, Burn J, Hovig E, Kloor M, Sampson JR, Dominguez-Valentin M; Prospective Lynch Syndrome Database (www.plsd.eu) and The European Hereditary Tumour Group (www.ehtg.org). Møller P, et al. Among authors: seppala tt. Hered Cancer Clin Pract. 2023 Oct 11;21(1):19. doi: 10.1186/s13053-023-00263-3. Hered Cancer Clin Pract. 2023. PMID: 37821984 Free PMC article. Review.
Quantitative Multiplexed Analysis of Indoleamine 2,3-Dioxygenase (IDO) and Arginase-1 (ARG1) Expression and Myeloid Cell Infiltration in Colorectal Cancer.
Elomaa H, Härkönen J, Väyrynen SA, Ahtiainen M, Ogino S, Nowak JA, Lau MC, Helminen O, Wirta EV, Seppälä TT, Böhm J, Mecklin JP, Kuopio T, Väyrynen JP. Elomaa H, et al. Among authors: seppala tt. Mod Pathol. 2024 Apr;37(4):100450. doi: 10.1016/j.modpat.2024.100450. Epub 2024 Feb 16. Mod Pathol. 2024. PMID: 38369188 Free article.
78 results