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Impaired IRE1α/XBP-1 pathway associated to DNA methylation might contribute to salivary gland dysfunction in Sjögren's syndrome patients.
Sepúlveda D, Barrera MJ, Castro I, Aguilera S, Carvajal P, Lagos C, González S, Albornoz N, Bahamondes V, Quest AFG, Urzúa U, Molina C, Leyton C, Hermoso MA, González MJ. Sepúlveda D, et al. Rheumatology (Oxford). 2018 Jun 1;57(6):1021-1032. doi: 10.1093/rheumatology/key021. Rheumatology (Oxford). 2018. PMID: 29534223
Oral dryness in Sjögren's syndrome patients. Not just a question of water.
Castro I, Sepúlveda D, Cortés J, Quest AF, Barrera MJ, Bahamondes V, Aguilera S, Urzúa U, Alliende C, Molina C, González S, Hermoso MA, Leyton C, González MJ. Castro I, et al. Among authors: sepulveda d. Autoimmun Rev. 2013 Mar;12(5):567-74. doi: 10.1016/j.autrev.2012.10.018. Epub 2012 Nov 30. Autoimmun Rev. 2013. PMID: 23207284
Sjögren's syndrome and the epithelial target: a comprehensive review.
Barrera MJ, Bahamondes V, Sepúlveda D, Quest AF, Castro I, Cortés J, Aguilera S, Urzúa U, Molina C, Pérez P, Ewert P, Alliende C, Hermoso MA, González S, Leyton C, González MJ. Barrera MJ, et al. Among authors: sepulveda d. J Autoimmun. 2013 May;42:7-18. doi: 10.1016/j.jaut.2013.02.001. Epub 2013 Mar 13. J Autoimmun. 2013. PMID: 23497939 Review.
Oral manifestations and their treatment in Sjögren's syndrome.
González S, Sung H, Sepúlveda D, González M, Molina C. González S, et al. Among authors: sepulveda d. Oral Dis. 2014 Mar;20(2):153-61. doi: 10.1111/odi.12105. Epub 2013 Apr 5. Oral Dis. 2014. PMID: 23557026 Review.
Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis.
Groenendyk J, Peng Z, Dudek E, Fan X, Mizianty MJ, Dufey E, Urra H, Sepulveda D, Rojas-Rivera D, Lim Y, Kim DH, Baretta K, Srikanth S, Gwack Y, Ahnn J, Kaufman RJ, Lee SK, Hetz C, Kurgan L, Michalak M. Groenendyk J, et al. Among authors: sepulveda d. Sci Signal. 2014 Jun 10;7(329):ra54. doi: 10.1126/scisignal.2004983. Sci Signal. 2014. PMID: 24917591 Free PMC article.
Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response.
Dufey E, Bravo-San Pedro JM, Eggers C, González-Quiroz M, Urra H, Sagredo AI, Sepulveda D, Pihán P, Carreras-Sureda A, Hazari Y, Sagredo EA, Gutierrez D, Valls C, Papaioannou A, Acosta-Alvear D, Campos G, Domingos PM, Pedeux R, Chevet E, Alvarez A, Godoy P, Walter P, Glavic A, Kroemer G, Hetz C. Dufey E, et al. Among authors: sepulveda d. Nat Commun. 2020 May 14;11(1):2401. doi: 10.1038/s41467-020-15694-y. Nat Commun. 2020. PMID: 32409639 Free PMC article.
Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α.
Sepulveda D, Rojas-Rivera D, Rodríguez DA, Groenendyk J, Köhler A, Lebeaupin C, Ito S, Urra H, Carreras-Sureda A, Hazari Y, Vasseur-Cognet M, Ali MMU, Chevet E, Campos G, Godoy P, Vaisar T, Bailly-Maitre B, Nagata K, Michalak M, Sierralta J, Hetz C. Sepulveda D, et al. Mol Cell. 2018 Jan 18;69(2):238-252.e7. doi: 10.1016/j.molcel.2017.12.028. Mol Cell. 2018. PMID: 29351844 Free article.
156 results