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Year Number of Results
2019 1
2020 3
2021 4
2022 9
2023 3
2024 0

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15 results

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Page 1
Fe65-engineered neuronal exosomes encapsulating corynoxine-B ameliorate cognition and pathology of Alzheimer's disease.
Iyaswamy A, Thakur A, Guan XJ, Krishnamoorthi S, Fung TY, Lu K, Gaurav I, Yang Z, Su CF, Lau KF, Zhang K, Ng RC, Lian Q, Cheung KH, Ye K, Chen HJ, Li M. Iyaswamy A, et al. Among authors: krishnamoorthi s. Signal Transduct Target Ther. 2023 Oct 23;8(1):404. doi: 10.1038/s41392-023-01657-4. Signal Transduct Target Ther. 2023. PMID: 37867176 Free PMC article.
PPARɑ Ligand Caudatin Improves Cognitive Functions and Mitigates Alzheimer's Disease Defects By Inducing Autophagy in Mice Models.
Krishnamoorthi S, Iyaswamy A, Sreenivasmurthy SG, Thakur A, Vasudevan K, Kumar G, Guan XJ, Lu K, Gaurav I, Su CF, Zhu Z, Liu J, Kan Y, Jayaraman S, Deng Z, Chua KK, Cheung KH, Yang Z, Song JX, Li M. Krishnamoorthi S, et al. J Neuroimmune Pharmacol. 2023 Sep;18(3):509-528. doi: 10.1007/s11481-023-10083-w. Epub 2023 Sep 8. J Neuroimmune Pharmacol. 2023. PMID: 37682502
Reduction of kinesin I heavy chain decreases tau hyperphosphorylation, aggregation, and memory impairment in Alzheimer's disease and tauopathy models.
Selvarasu K, Singh AK, Iyaswamy A, Gopalkrishnashetty Sreenivasmurthy S, Krishnamoorthi S, Bera AK, Huang JD, Durairajan SSK. Selvarasu K, et al. Among authors: krishnamoorthi s. Front Mol Biosci. 2022 Oct 25;9:1050768. doi: 10.3389/fmolb.2022.1050768. eCollection 2022. Front Mol Biosci. 2022. PMID: 36387285 Free PMC article.
Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer's disease therapy.
Sreenivasmurthy SG, Iyaswamy A, Krishnamoorthi S, Reddi RN, Kammala AK, Vasudevan K, Senapati S, Zhu Z, Su CF, Liu J, Guan XJ, Chua KK, Cheung KH, Chen H, Zhang HJ, Zhang Y, Song JX, Kumar Durairajan SS, Li M. Sreenivasmurthy SG, et al. Among authors: krishnamoorthi s. Front Mol Biosci. 2022 Oct 26;9:1030534. doi: 10.3389/fmolb.2022.1030534. eCollection 2022. Front Mol Biosci. 2022. PMID: 36387280 Free PMC article.
Real-Time Detection and Visualization of Amyloid-β Aggregates Induced by Hydrogen Peroxide in Cell and Mouse Models of Alzheimer's Disease.
Wang X, Iyaswamy A, Xu D, Krishnamoorthi S, Sreenivasmurthy SG, Yang Y, Li Y, Chen C, Li M, Li HW, Wong MS. Wang X, et al. Among authors: krishnamoorthi s. ACS Appl Mater Interfaces. 2023 Jan 11;15(1):39-47. doi: 10.1021/acsami.2c07859. Epub 2022 Jul 22. ACS Appl Mater Interfaces. 2023. PMID: 35866616 Free PMC article. Review.
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models.
Iyaswamy A, Wang X, Krishnamoorthi S, Kaliamoorthy V, Sreenivasmurthy SG, Kumar Durairajan SS, Song JX, Tong BC, Zhu Z, Su CF, Liu J, Cheung KH, Lu JH, Tan JQ, Li HW, Wong MS, Li M. Iyaswamy A, et al. Among authors: krishnamoorthi s. Redox Biol. 2022 May;51:102280. doi: 10.1016/j.redox.2022.102280. Epub 2022 Mar 8. Redox Biol. 2022. PMID: 35286997 Free PMC article.
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy.
Zhu Z, Liu LF, Su CF, Liu J, Tong BC, Iyaswamy A, Krishnamoorthi S, Sreenivasmurthy SG, Guan XJ, Kan YX, Xie WJ, Zhao CL, Cheung KH, Lu JH, Tan JQ, Zhang HJ, Song JX, Li M. Zhu Z, et al. Among authors: krishnamoorthi s. Acta Pharmacol Sin. 2022 Oct;43(10):2511-2526. doi: 10.1038/s41401-022-00871-0. Epub 2022 Feb 25. Acta Pharmacol Sin. 2022. PMID: 35217810 Free PMC article.
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition.
Sreenivasmurthy SG, Iyaswamy A, Krishnamoorthi S, Senapati S, Malampati S, Zhu Z, Su CF, Liu J, Guan XJ, Tong BC, Cheung KH, Tan JQ, Lu JH, Durairajan SSK, Song JX, Li M. Sreenivasmurthy SG, et al. Among authors: krishnamoorthi s. Phytomedicine. 2022 Feb;96:153887. doi: 10.1016/j.phymed.2021.153887. Epub 2021 Dec 8. Phytomedicine. 2022. PMID: 34936968
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2.
Yang CB, Liu J, Tong BC, Wang ZY, Zhu Z, Su CF, Sreenivasmurthy SG, Wu JX, Iyaswamy A, Krishnamoorthi S, Huang SY, Cheung KH, Song JX, Tan JQ, Lu JH, Li M. Yang CB, et al. Among authors: krishnamoorthi s. Acta Pharmacol Sin. 2022 May;43(5):1251-1263. doi: 10.1038/s41401-021-00711-7. Epub 2021 Aug 20. Acta Pharmacol Sin. 2022. PMID: 34417577 Free PMC article.
15 results