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Page 1
Development of potent monoclonal antibody auristatin conjugates for cancer therapy.
Doronina SO, Toki BE, Torgov MY, Mendelsohn BA, Cerveny CG, Chace DF, DeBlanc RL, Gearing RP, Bovee TD, Siegall CB, Francisco JA, Wahl AF, Meyer DL, Senter PD. Doronina SO, et al. Among authors: senter pd. Nat Biotechnol. 2003 Jul;21(7):778-84. doi: 10.1038/nbt832. Epub 2003 Jun 1. Nat Biotechnol. 2003. PMID: 12778055
Efficient elimination of B-lineage lymphomas by anti-CD20-auristatin conjugates.
Law CL, Cerveny CG, Gordon KA, Klussman K, Mixan BJ, Chace DF, Meyer DL, Doronina SO, Siegall CB, Francisco JA, Senter PD, Wahl AF. Law CL, et al. Among authors: senter pd. Clin Cancer Res. 2004 Dec 1;10(23):7842-51. doi: 10.1158/1078-0432.CCR-04-1028. Clin Cancer Res. 2004. PMID: 15585616
Dipeptide-based highly potent doxorubicin antibody conjugates.
Jeffrey SC, Nguyen MT, Andreyka JB, Meyer DL, Doronina SO, Senter PD. Jeffrey SC, et al. Among authors: senter pd. Bioorg Med Chem Lett. 2006 Jan 15;16(2):358-62. doi: 10.1016/j.bmcl.2005.09.081. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16275070
Lysosomal trafficking and cysteine protease metabolism confer target-specific cytotoxicity by peptide-linked anti-CD30-auristatin conjugates.
Sutherland MS, Sanderson RJ, Gordon KA, Andreyka J, Cerveny CG, Yu C, Lewis TS, Meyer DL, Zabinski RF, Doronina SO, Senter PD, Law CL, Wahl AF. Sutherland MS, et al. Among authors: senter pd. J Biol Chem. 2006 Apr 14;281(15):10540-7. doi: 10.1074/jbc.M510026200. Epub 2006 Feb 16. J Biol Chem. 2006. PMID: 16484228 Free article.
Lymphocyte activation antigen CD70 expressed by renal cell carcinoma is a potential therapeutic target for anti-CD70 antibody-drug conjugates.
Law CL, Gordon KA, Toki BE, Yamane AK, Hering MA, Cerveny CG, Petroziello JM, Ryan MC, Smith L, Simon R, Sauter G, Oflazoglu E, Doronina SO, Meyer DL, Francisco JA, Carter P, Senter PD, Copland JA, Wood CG, Wahl AF. Law CL, et al. Among authors: senter pd. Cancer Res. 2006 Feb 15;66(4):2328-37. doi: 10.1158/0008-5472.CAN-05-2883. Cancer Res. 2006. PMID: 16489038
Novel peptide linkers for highly potent antibody-auristatin conjugate.
Doronina SO, Bovee TD, Meyer DW, Miyamoto JB, Anderson ME, Morris-Tilden CA, Senter PD. Doronina SO, et al. Among authors: senter pd. Bioconjug Chem. 2008 Oct;19(10):1960-3. doi: 10.1021/bc800289a. Epub 2008 Sep 20. Bioconjug Chem. 2008. PMID: 18803412
135 results