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Nanomedicine platform for targeting activated neutrophils and neutrophil-platelet complexes using an α1-antitrypsin-derived peptide motif.
Cruz MA, Bohinc D, Andraska EA, Alvikas J, Raghunathan S, Masters NA, van Kleef ND, Bane KL, Hart K, Medrow K, Sun M, Liu H, Haldeman S, Banerjee A, Lessieur EM, Hageman K, Gandhi A, de la Fuente M, Nieman MT, Kern TS, Maas C, de Maat S, Neeves KB, Neal MD, Sen Gupta A, Stavrou EX. Cruz MA, et al. Among authors: sen gupta a. Nat Nanotechnol. 2022 Sep;17(9):1004-1014. doi: 10.1038/s41565-022-01161-w. Epub 2022 Jul 18. Nat Nanotechnol. 2022. PMID: 35851383 Free PMC article.
Ferric Chloride-induced Murine Thrombosis Models.
Li W, Nieman M, Sen Gupta A. Li W, et al. Among authors: sen gupta a. J Vis Exp. 2016 Sep 5;(115):54479. doi: 10.3791/54479. J Vis Exp. 2016. PMID: 27684194 Free PMC article.
Factor XII and uPAR upregulate neutrophil functions to influence wound healing.
Stavrou EX, Fang C, Bane KL, Long AT, Naudin C, Kucukal E, Gandhi A, Brett-Morris A, Mumaw MM, Izadmehr S, Merkulova A, Reynolds CC, Alhalabi O, Nayak L, Yu WM, Qu CK, Meyerson HJ, Dubyak GR, Gurkan UA, Nieman MT, Sen Gupta A, Renné T, Schmaier AH. Stavrou EX, et al. Among authors: sen gupta a. J Clin Invest. 2018 Mar 1;128(3):944-959. doi: 10.1172/JCI92880. Epub 2018 Jan 29. J Clin Invest. 2018. PMID: 29376892 Free PMC article.
Intravenous synthetic platelet (SynthoPlate) nanoconstructs reduce bleeding and improve 'golden hour' survival in a porcine model of traumatic arterial hemorrhage.
Hickman DA, Pawlowski CL, Shevitz A, Luc NF, Kim A, Girish A, Marks J, Ganjoo S, Huang S, Niedoba E, Sekhon UDS, Sun M, Dyer M, Neal MD, Kashyap VS, Sen Gupta A. Hickman DA, et al. Among authors: sen gupta a. Sci Rep. 2018 Feb 15;8(1):3118. doi: 10.1038/s41598-018-21384-z. Sci Rep. 2018. PMID: 29449604 Free PMC article.
150 results