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The TLR2/TLR6 ligand FSL-1 mitigates radiation-induced hematopoietic injury in mice and nonhuman primates.
Brickey WJ, Caudell DL, Macintyre AN, Olson JD, Dai Y, Li S, Dugan GO, Bourland JD, O'Donnell LM, Tooze JA, Huang G, Yang S, Guo H, French MN, Schorzman AN, Zamboni WC, Sempowski GD, Li Z, Owzar K, Chao NJ, Cline JM, Ting JPY. Brickey WJ, et al. Among authors: sempowski gd. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2122178120. doi: 10.1073/pnas.2122178120. Epub 2023 Dec 5. Proc Natl Acad Sci U S A. 2023. PMID: 38051771
Growth hormone mitigates against lethal irradiation and enhances hematologic and immune recovery in mice and nonhuman primates.
Chen BJ, Deoliveira D, Spasojevic I, Sempowski GD, Jiang C, Owzar K, Wang X, Gesty-Palmer D, Cline JM, Bourland JD, Dugan G, Meadows SK, Daher P, Muramoto G, Chute JP, Chao NJ. Chen BJ, et al. Among authors: sempowski gd. PLoS One. 2010 Jun 16;5(6):e11056. doi: 10.1371/journal.pone.0011056. PLoS One. 2010. PMID: 20585403 Free PMC article.
Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites.
Guo H, Chou WC, Lai Y, Liang K, Tam JW, Brickey WJ, Chen L, Montgomery ND, Li X, Bohannon LM, Sung AD, Chao NJ, Peled JU, Gomes ALC, van den Brink MRM, French MJ, Macintyre AN, Sempowski GD, Tan X, Sartor RB, Lu K, Ting JPY. Guo H, et al. Among authors: sempowski gd. Science. 2020 Oct 30;370(6516):eaay9097. doi: 10.1126/science.aay9097. Science. 2020. PMID: 33122357 Free PMC article.
MyD88 provides a protective role in long-term radiation-induced lung injury.
Brickey WJ, Neuringer IP, Walton W, Hua X, Wang EY, Jha S, Sempowski GD, Yang X, Kirby SL, Tilley SL, Ting JP. Brickey WJ, et al. Among authors: sempowski gd. Int J Radiat Biol. 2012 Apr;88(4):335-47. doi: 10.3109/09553002.2012.652723. Epub 2012 Feb 6. Int J Radiat Biol. 2012. PMID: 22248128 Free PMC article.
200 results