Semenza GL - Search Results

1

ZBTB2 links p53 deficiency to HIF-1-mediated hypoxia signaling to promote cancer aggressiveness.

Koyasu S, Horita S, Saito K, Kobayashi M, Ishikita H, Chow CC, Kambe G, Nishikawa S, Menju T, Morinibu A, Okochi Y, Tabuchi Y, Onodera Y, Takeda N, Date H, Semenza GL, Hammond EM, Harada H. Koyasu S, et al. Among authors: semenza gl. EMBO Rep. 2023 Jan 9;24(1):e54042. doi: 10.15252/embr.202154042. Epub 2022 Nov 7. EMBO Rep. 2023. PMID: 36341521 Free PMC article.

2

p53 does not repress hypoxia-induced transcription of the vascular endothelial growth factor gene.

Agani F, Kirsch DG, Friedman SL, Kastan MB, Semenza GL. Agani F, et al. Among authors: semenza gl. Cancer Res. 1997 Oct 15;57(20):4474-7. Cancer Res. 1997. PMID: 9377555

3

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha.

Ravi R, Mookerjee B, Bhujwalla ZM, Sutter CH, Artemov D, Zeng Q, Dillehay LE, Madan A, Semenza GL, Bedi A. Ravi R, et al. Among authors: semenza gl. Genes Dev. 2000 Jan 1;14(1):34-44. Genes Dev. 2000. PMID: 10640274 Free PMC article.

4

Hypoxia, HIF-1, and the pathophysiology of common human diseases.

Semenza GL, Agani F, Feldser D, Iyer N, Kotch L, Laughner E, Yu A. Semenza GL, et al. Adv Exp Med Biol. 2000;475:123-30. doi: 10.1007/0-306-46825-5_12. Adv Exp Med Biol. 2000. PMID: 10849654 Review.

5

HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression.

Laughner E, Taghavi P, Chiles K, Mahon PC, Semenza GL. Laughner E, et al. Among authors: semenza gl. Mol Cell Biol. 2001 Jun;21(12):3995-4004. doi: 10.1128/MCB.21.12.3995-4004.2001. Mol Cell Biol. 2001. PMID: 11359907 Free PMC article.

6

HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus.

Semenza GL. Semenza GL. Cell. 2001 Oct 5;107(1):1-3. doi: 10.1016/s0092-8674(01)00518-9. Cell. 2001. PMID: 11595178 Free article. Review.

7

Involvement of hypoxia-inducible factor 1 in human cancer.

Semenza GL. Semenza GL. Intern Med. 2002 Feb;41(2):79-83. doi: 10.2169/internalmedicine.41.79. Intern Med. 2002. PMID: 11868612 Free article.

8

Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells.

Fukuda R, Hirota K, Fan F, Jung YD, Ellis LM, Semenza GL. Fukuda R, et al. Among authors: semenza gl. J Biol Chem. 2002 Oct 11;277(41):38205-11. doi: 10.1074/jbc.M203781200. Epub 2002 Jul 30. J Biol Chem. 2002. PMID: 12149254 Free article.

9

Targeting HIF-1 for cancer therapy.

Semenza GL. Semenza GL. Nat Rev Cancer. 2003 Oct;3(10):721-32. doi: 10.1038/nrc1187. Nat Rev Cancer. 2003. PMID: 13130303 Review.

10

OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.

Baek JH, Mahon PC, Oh J, Kelly B, Krishnamachary B, Pearson M, Chan DA, Giaccia AJ, Semenza GL. Baek JH, et al. Among authors: semenza gl. Mol Cell. 2005 Feb 18;17(4):503-12. doi: 10.1016/j.molcel.2005.01.011. Mol Cell. 2005. PMID: 15721254 Free article.

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