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Physiologically-based pharmacokinetic modeling of quinidine to establish a CYP3A4, P-gp, and CYP2D6 drug-drug-gene interaction network.
Feick D, Rüdesheim S, Marok FZ, Selzer D, Loer HLH, Teutonico D, Frechen S, van der Lee M, Moes DJAR, Swen JJ, Schwab M, Lehr T. Feick D, et al. Among authors: selzer d. CPT Pharmacometrics Syst Pharmacol. 2023 Aug;12(8):1143-1156. doi: 10.1002/psp4.12981. Epub 2023 May 23. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37165978 Free PMC article.
Nanocarriers for optimizing the balance between interfollicular permeation and follicular uptake of topically applied clobetasol to minimize adverse effects.
Mathes C, Melero A, Conrad P, Vogt T, Rigo L, Selzer D, Prado WA, De Rossi C, Garrigues TM, Hansen S, Guterres SS, Pohlmann AR, Beck RCR, Lehr CM, Schaefer UF. Mathes C, et al. Among authors: selzer d. J Control Release. 2016 Feb 10;223:207-214. doi: 10.1016/j.jconrel.2015.12.010. Epub 2015 Dec 11. J Control Release. 2016. PMID: 26686081 Free article.
Mathematical models for dermal drug absorption.
Selzer D, Neumann D, Schaefer UF. Selzer D, et al. Expert Opin Drug Metab Toxicol. 2015;11(10):1567-83. doi: 10.1517/17425255.2015.1063615. Epub 2015 Jul 13. Expert Opin Drug Metab Toxicol. 2015. PMID: 26166490 Review.
An extended database of keratin binding.
Hansen S, Selzer D, Schaefer UF, Kasting GB. Hansen S, et al. Among authors: selzer d. J Pharm Sci. 2011 May;100(5):1712-26. doi: 10.1002/jps.22396. Epub 2010 Nov 30. J Pharm Sci. 2011. PMID: 21374609
A strategy for in-silico prediction of skin absorption in man.
Selzer D, Neumann D, Neumann H, Kostka KH, Lehr CM, Schaefer UF. Selzer D, et al. Eur J Pharm Biopharm. 2015 Sep;95(Pt A):68-76. doi: 10.1016/j.ejpb.2015.05.002. Epub 2015 May 29. Eur J Pharm Biopharm. 2015. PMID: 26022643
102 results