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Reactivation of mutant p53 through interaction of a C-terminal peptide with the core domain.
Selivanova G, Ryabchenko L, Jansson E, Iotsova V, Wiman KG. Selivanova G, et al. Mol Cell Biol. 1999 May;19(5):3395-402. doi: 10.1128/MCB.19.5.3395. Mol Cell Biol. 1999. PMID: 10207063 Free PMC article.
A synthetic 22-mer peptide (peptide 46) derived from the p53 C-terminal domain can restore the growth suppressor function of mutant p53 proteins in human tumor cells (G. Selivanova et al., Nat. Med. 3:632-638, 1997). Here we demonstrate that peptide 46 binds mutant …
A synthetic 22-mer peptide (peptide 46) derived from the p53 C-terminal domain can restore the growth suppressor function of mutant p53 prot …
p53 induction as an indicator of DNA damage.
Selivanova G. Selivanova G. Methods Mol Biol. 2002;203:279-88. doi: 10.1385/1-59259-179-5:279. Methods Mol Biol. 2002. PMID: 12073449 No abstract available.
p53: fighting cancer.
Selivanova G. Selivanova G. Curr Cancer Drug Targets. 2004 Aug;4(5):385-402. doi: 10.2174/1568009043332934. Curr Cancer Drug Targets. 2004. PMID: 15320716 Review.
159 results