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Sex differences in heart mitochondria regulate diastolic dysfunction.
Cao Y, Vergnes L, Wang YC, Pan C, Chella Krishnan K, Moore TM, Rosa-Garrido M, Kimball TH, Zhou Z, Charugundla S, Rau CD, Seldin MM, Wang J, Wang Y, Vondriska TM, Reue K, Lusis AJ. Cao Y, et al. Among authors: seldin mm. Nat Commun. 2022 Jul 4;13(1):3850. doi: 10.1038/s41467-022-31544-5. Nat Commun. 2022. PMID: 35787630 Free PMC article.
Multi-omics approaches to disease.
Hasin Y, Seldin M, Lusis A. Hasin Y, et al. Genome Biol. 2017 May 5;18(1):83. doi: 10.1186/s13059-017-1215-1. Genome Biol. 2017. PMID: 28476144 Free PMC article. Review.
Epigenome-wide association in adipose tissue from the METSIM cohort.
Orozco LD, Farrell C, Hale C, Rubbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Boehnke M, Mohlke KL, Jacobsen S, Kuusisto J, Laakso M, Lusis AJ, Pellegrini M. Orozco LD, et al. Hum Mol Genet. 2018 May 15;27(10):1830-1846. doi: 10.1093/hmg/ddy093. Hum Mol Genet. 2018. PMID: 29566149 Free PMC article.
Epigenome-wide association in adipose tissue from the METSIM cohort.
Orozco LD, Farrell C, Hale C, Rubbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Boehnke M, Mohlke KL, Jacobsen S, Kuusisto J, Laakso M, Lusis AJ, Pellegrini M. Orozco LD, et al. Hum Mol Genet. 2018 Jul 15;27(14):2586. doi: 10.1093/hmg/ddy205. Hum Mol Genet. 2018. PMID: 29893869 Free PMC article. No abstract available.
FAM13A affects body fat distribution and adipocyte function.
Fathzadeh M, Li J, Rao A, Cook N, Chennamsetty I, Seldin M, Zhou X, Sangwung P, Gloudemans MJ, Keller M, Attie A, Yang J, Wabitsch M, Carcamo-Orive I, Tada Y, Lusis AJ, Shin MK, Molony CM, McLaughlin T, Reaven G, Montgomery SB, Reilly D, Quertermous T, Ingelsson E, Knowles JW. Fathzadeh M, et al. Nat Commun. 2020 Mar 19;11(1):1465. doi: 10.1038/s41467-020-15291-z. Nat Commun. 2020. PMID: 32193374 Free PMC article.
Systems genetics applications in metabolism research.
Seldin M, Yang X, Lusis AJ. Seldin M, et al. Nat Metab. 2019 Nov;1(11):1038-1050. doi: 10.1038/s42255-019-0132-x. Epub 2019 Oct 21. Nat Metab. 2019. PMID: 32259026 Free PMC article. Review.
Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury.
Yokota T, McCourt J, Ma F, Ren S, Li S, Kim TH, Kurmangaliyev YZ, Nasiri R, Ahadian S, Nguyen T, Tan XHM, Zhou Y, Wu R, Rodriguez A, Cohn W, Wang Y, Whitelegge J, Ryazantsev S, Khademhosseini A, Teitell MA, Chiou PY, Birk DE, Rowat AC, Crosbie RH, Pellegrini M, Seldin M, Lusis AJ, Deb A. Yokota T, et al. Cell. 2020 Aug 6;182(3):545-562.e23. doi: 10.1016/j.cell.2020.06.030. Epub 2020 Jul 3. Cell. 2020. PMID: 32621799 Free PMC article.
Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling.
Zhou Z, Moore TM, Drew BG, Ribas V, Wanagat J, Civelek M, Segawa M, Wolf DM, Norheim F, Seldin MM, Strumwasser AR, Whitney KA, Lester E, Reddish BR, Vergnes L, Reue K, Rajbhandari P, Tontonoz P, Lee J, Mahata SK, Hewitt SC, Shirihai O, Gastonbury C, Small KS, Laakso M, Jensen J, Lee S, Drevon CA, Korach KS, Lusis AJ, Hevener AL. Zhou Z, et al. Among authors: seldin mm. Sci Transl Med. 2020 Aug 5;12(555):eaax8096. doi: 10.1126/scitranslmed.aax8096. Sci Transl Med. 2020. PMID: 32759275 Free PMC article.
Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis.
Norheim F, Chella Krishnan K, Bjellaas T, Vergnes L, Pan C, Parks BW, Meng Y, Lang J, Ward JA, Reue K, Mehrabian M, Gundersen TE, Péterfy M, Dalen KT, Drevon CA, Hui ST, Lusis AJ, Seldin MM. Norheim F, et al. Among authors: seldin mm. Mol Syst Biol. 2021 Jan;17(1):e9684. doi: 10.15252/msb.20209684. Mol Syst Biol. 2021. PMID: 33417276 Free PMC article.
75 results