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Melatonin is a potential drug for the prevention of bone loss during space flight.
Ikegame M, Hattori A, Tabata MJ, Kitamura KI, Tabuchi Y, Furusawa Y, Maruyama Y, Yamamoto T, Sekiguchi T, Matsuoka R, Hanmoto T, Ikari T, Endo M, Omori K, Nakano M, Yashima S, Ejiri S, Taya T, Nakashima H, Shimizu N, Nakamura M, Kondo T, Hayakawa K, Takasaki I, Kaminishi A, Akatsuka R, Sasayama Y, Nishiuchi T, Nara M, Iseki H, Chowdhury VS, Wada S, Ijiri K, Takeuchi T, Suzuki T, Ando H, Matsuda K, Somei M, Mishima H, Mikuni-Takagaki Y, Funahashi H, Takahashi A, Watanabe Y, Maeda M, Uchida H, Hayashi A, Kambegawa A, Seki A, Yano S, Shimazu T, Suzuki H, Hirayama J, Suzuki N. Ikegame M, et al. Among authors: sekiguchi t. J Pineal Res. 2019 Oct;67(3):e12594. doi: 10.1111/jpi.12594. Epub 2019 Jul 19. J Pineal Res. 2019. PMID: 31286565 Free PMC article.
Oral administration of melatonin contained in drinking water increased bone strength in naturally aged mice.
Igarashi-Migitaka J, Seki A, Ikegame M, Honda M, Sekiguchi T, Mishima H, Shimizu N, Matsubara H, Srivastav AK, Hirayama J, Maruyama Y, Kamijo-Ikemori A, Hirata K, Hattori A, Suzuki N. Igarashi-Migitaka J, et al. Among authors: sekiguchi t. Acta Histochem. 2020 Sep;122(6):151596. doi: 10.1016/j.acthis.2020.151596. Epub 2020 Jul 18. Acta Histochem. 2020. PMID: 32778234
De novo transcriptome analysis and gene expression profiling of fish scales isolated from Carassius auratus during space flight: Impact of melatonin on gene expression in response to space radiation.
Furusawa Y, Yamamoto T, Hattori A, Suzuki N, Hirayama J, Sekiguchi T, Tabuchi Y. Furusawa Y, et al. Among authors: sekiguchi t. Mol Med Rep. 2020 Oct;22(4):2627-2636. doi: 10.3892/mmr.2020.11363. Epub 2020 Jul 28. Mol Med Rep. 2020. PMID: 32945420 Free PMC article.
Physiological consequences of space flight, including abnormal bone metabolism, space radiation injury, and circadian clock dysregulation: Implications of melatonin use and regulation as a countermeasure.
Hirayama J, Hattori A, Takahashi A, Furusawa Y, Tabuchi Y, Shibata M, Nagamatsu A, Yano S, Maruyama Y, Matsubara H, Sekiguchi T, Suzuki N. Hirayama J, et al. Among authors: sekiguchi t. J Pineal Res. 2023 Jan;74(1):e12834. doi: 10.1111/jpi.12834. Epub 2022 Oct 17. J Pineal Res. 2023. PMID: 36203395 Review.
Low-intensity pulsed ultrasound induces apoptosis in osteoclasts: Fish scales are a suitable model for the analysis of bone metabolism by ultrasound.
Suzuki N, Hanmoto T, Yano S, Furusawa Y, Ikegame M, Tabuchi Y, Kondo T, Kitamura K, Endo M, Yamamoto T, Sekiguchi T, Urata M, Mikuni-Takagaki Y, Hattori A. Suzuki N, et al. Among authors: sekiguchi t. Comp Biochem Physiol A Mol Integr Physiol. 2016 May;195:26-31. doi: 10.1016/j.cbpa.2016.01.022. Epub 2016 Feb 2. Comp Biochem Physiol A Mol Integr Physiol. 2016. PMID: 26850473 Free article.
Polychlorinated biphenyl (118) activates osteoclasts and induces bone resorption in goldfish.
Yachiguchi K, Matsumoto N, Haga Y, Suzuki M, Matsumura C, Tsurukawa M, Okuno T, Nakano T, Kawabe K, Kitamura K, Toriba A, Hayakawa K, Chowdhury VS, Endo M, Chiba A, Sekiguchi T, Nakano M, Tabuchi Y, Kondo T, Wada S, Mishima H, Hattori A, Suzuki N. Yachiguchi K, et al. Among authors: sekiguchi t. Environ Sci Pollut Res Int. 2014 May;21(10):6365-72. doi: 10.1007/s11356-012-1347-5. Epub 2012 Dec 18. Environ Sci Pollut Res Int. 2014. PMID: 23247518 Free PMC article.
Static and dynamic hypergravity responses of osteoblasts and osteoclasts in medaka scales.
Yano S, Kitamura K, Satoh Y, Nakano M, Hattori A, Sekiguchi T, Ikegame M, Nakashima H, Omori K, Hayakawa K, Chiba A, Sasayama Y, Ejiri S, Mikuni-Takagaki Y, Mishima H, Funahashi H, Sakamoto T, Suzuki N. Yano S, et al. Among authors: sekiguchi t. Zoolog Sci. 2013 Mar;30(3):217-23. doi: 10.2108/zsj.30.217. Zoolog Sci. 2013. PMID: 23480382 Free article.
825 results