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Dose finding study for on-demand HIV pre-exposure prophylaxis for insertive sex in sub-Saharan Africa: results from the CHAPS open label randomised controlled trial.
EBioMedicine. 2023 Jul;93:104648. doi: 10.1016/j.ebiom.2023.104648. Epub 2023 Jun 14.
EBioMedicine. 2023.
PMID: 37327677
Free PMC article.
Clinical Trial.
Combined HIV Adolescent Prevention Study (CHAPS): comparison of HIV pre-exposure prophylaxis regimens for adolescents in sub-Saharan Africa-study protocol for a mixed-methods study including a randomised controlled trial.
Nash S, Dietrich J, Ssemata AS, Herrera C, O'Hagan K, Else L, Chiodi F, Kelly C, Shattock R, Chirenje M, Lebina L, Khoo S, Bekker LG, Weiss HA, Gray C, Stranix-Chibanda L, Kaleebu P, Seeley J, Martinson N, Fox J; CHAPS team.
Nash S, et al.
Trials. 2020 Oct 30;21(1):900. doi: 10.1186/s13063-020-04760-x.
Trials. 2020.
PMID: 33121503
Free PMC article.
Item in Clipboard
Mobilization of systemic CCL4 following HIV pre-exposure prophylaxis in young men in Africa.
Petkov S, Herrera C, Else L, Mugaba S, Namubiru P, Odoch G, Opoka D, Pillay AAP, Seiphetlo TB, Serwanga J, Ssemata AS, Kaleebu P, Webb EL, Khoo S, Lebina L, Gray CM, Martinson N, Fox J, Chiodi F.
Petkov S, et al. Among authors: seiphetlo tb.
Front Immunol. 2022 Jul 27;13:965214. doi: 10.3389/fimmu.2022.965214. eCollection 2022.
Front Immunol. 2022.
PMID: 35967369
Free PMC article.
Item in Clipboard
Pre-Clinical Evaluation of Tenofovir and Tenofovir Alafenamide for HIV-1 Pre-Exposure Prophylaxis in Foreskin Tissue.
Else L, Penchala SD, Pillay AD, Seiphetlo TB, Lebina L, Callebaut C, Minhas S, Morley R, Rashid T, Martinson N, Fox J, Khoo S, Herrera C; CHAPS Consortium.
Else L, et al. Among authors: seiphetlo tb.
Pharmaceutics. 2022 Jun 16;14(6):1285. doi: 10.3390/pharmaceutics14061285.
Pharmaceutics. 2022.
PMID: 35745857
Free PMC article.
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Short-term oral pre-exposure prophylaxis against HIV-1 modulates the transcriptome of foreskin tissue in young men in Africa.
Petkov S, Herrera C, Else L, Lebina L, Opoka D, Seiphetlo TB, Pillay AA, Mugaba S, Namubiru P, Odoch G, Ssemata AS, Serwanga J, Kaleebu P, Webb EL, Khoo S, Martinson N, Gray CM, Fox J, Chiodi F.
Petkov S, et al. Among authors: seiphetlo tb.
Front Immunol. 2022 Nov 18;13:1009978. doi: 10.3389/fimmu.2022.1009978. eCollection 2022.
Front Immunol. 2022.
PMID: 36479111
Free PMC article.
Clinical Trial.
Item in Clipboard
A randomized clinical trial of on-demand oral pre-exposure prophylaxis does not modulate lymphoid/myeloid HIV target cell density in the foreskin.
Rametse CL, Webb EL, Herrera C, Alinde B, Besethi A, Motaung B, Mbangiwa T, Leach L, Sebaa S, Pillay AAP, Seiphetlo TB, Malhangu B, Petkov S, Else L, Mugaba S, Namubiru P, Odoch G, Opoka D, Serwanga J, Ssemata AS, Kaleebu P, Khoo S, Lebina L, Martinson N, Chiodi F, Fox J, Gray CM; CHAPS consortium.
Rametse CL, et al. Among authors: seiphetlo tb.
AIDS. 2023 Sep 1;37(11):1651-1659. doi: 10.1097/QAD.0000000000003619. Epub 2023 Jun 6.
AIDS. 2023.
PMID: 37289572
Clinical Trial.
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Proteomic Analysis of Mucosal and Systemic Responses to SARS-CoV-2 Antigen.
Martinson N, Gordhan B, Petkov S, Pillay AD, Seiphetlo T, Singh N, Otwombe K, Lebina L, Fredolini C, Chiodi F, Fox J, Kana B, Herrera C.
Martinson N, et al.
Vaccines (Basel). 2023 Feb 2;11(2):334. doi: 10.3390/vaccines11020334.
Vaccines (Basel). 2023.
PMID: 36851212
Free PMC article.
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