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Effective treatment of human breast tumor in a mouse xenograft model with herpes simplex virus type 1 specifying the NV1020 genomic deletion and the gBsyn3 syncytial mutation enabling high viral replication and spread in breast cancer cells.
Israyelyan AH, Melancon JM, Lomax LG, Sehgal I, Leuschner C, Kearney MT, Chouljenko VN, Baghian A, Kousoulas KG. Israyelyan AH, et al. Among authors: sehgal i. Hum Gene Ther. 2007 May;18(5):457-73. doi: 10.1089/hum.2006.145. Hum Gene Ther. 2007. PMID: 17536976
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