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Page 1
p107 acts as a tumor suppressor in pRb-deficient epidermis.
Lara MF, Santos M, Ruiz S, Segrelles C, Moral M, Martínez-Cruz AB, Hernández P, Martínez-Palacio J, Lorz C, García-Escudero R, Paramio JM. Lara MF, et al. Among authors: segrelles c. Mol Carcinog. 2008 Feb;47(2):105-13. doi: 10.1002/mc.20367. Mol Carcinog. 2008. PMID: 17932945
Deregulated activity of Akt in epithelial basal cells induces spontaneous tumors and heightened sensitivity to skin carcinogenesis.
Segrelles C, Lu J, Hammann B, Santos M, Moral M, Cascallana JL, Lara MF, Rho O, Carbajal S, Traag J, Beltrán L, Martínez-Cruz AB, García-Escudero R, Lorz C, Ruiz S, Bravo A, Paramio JM, DiGiovanni J. Segrelles C, et al. Cancer Res. 2007 Nov 15;67(22):10879-88. doi: 10.1158/0008-5472.CAN-07-2564. Cancer Res. 2007. PMID: 18006833
Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma.
Moral M, Segrelles C, Lara MF, Martínez-Cruz AB, Lorz C, Santos M, García-Escudero R, Lu J, Kiguchi K, Buitrago A, Costa C, Saiz C, Rodriguez-Peralto JL, Martinez-Tello FJ, Rodriguez-Pinilla M, Sanchez-Cespedes M, Garín M, Grande T, Bravo A, DiGiovanni J, Paramio JM. Moral M, et al. Among authors: segrelles c. Cancer Res. 2009 Feb 1;69(3):1099-108. doi: 10.1158/0008-5472.CAN-08-3240. Epub 2009 Jan 27. Cancer Res. 2009. PMID: 19176372 Free PMC article.
On the origin of epidermal cancers.
Lorz C, Segrelles C, Paramio JM. Lorz C, et al. Among authors: segrelles c. Curr Mol Med. 2009 Apr;9(3):353-64. doi: 10.2174/156652409787847227. Curr Mol Med. 2009. PMID: 19355916 Review.
55 results