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Generation of NKX2.5GFP Reporter Human iPSCs and Differentiation Into Functional Cardiac Fibroblasts.
López-Muneta L, Linares J, Casis O, Martínez-Ibáñez L, González Miqueo A, Bezunartea J, Sanchez de la Nava AM, Gallego M, Fernández-Santos ME, Rodriguez-Madoz JR, Aranguren XL, Fernández-Avilés F, Segovia JC, Prósper F, Carvajal-Vergara X. López-Muneta L, et al. Among authors: segovia jc. Front Cell Dev Biol. 2022 Jan 21;9:797927. doi: 10.3389/fcell.2021.797927. eCollection 2021. Front Cell Dev Biol. 2022. PMID: 35127713 Free PMC article.
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Garate Z, Quintana-Bustamante O, Crane AM, Olivier E, Poirot L, Galetto R, Kosinski P, Hill C, Kung C, Agirre X, Orman I, Cerrato L, Alberquilla O, Rodriguez-Fornes F, Fusaki N, Garcia-Sanchez F, Maia TM, Ribeiro ML, Sevilla J, Prosper F, Jin S, Mountford J, Guenechea G, Gouble A, Bueren JA, Davis BR, Segovia JC. Garate Z, et al. Among authors: segovia jc. Stem Cell Reports. 2015 Dec 8;5(6):1053-1066. doi: 10.1016/j.stemcr.2015.10.002. Epub 2015 Nov 5. Stem Cell Reports. 2015. PMID: 26549847 Free PMC article.
The Current Status of Mesenchymal Stromal Cells: Controversies, Unresolved Issues and Some Promising Solutions to Improve Their Therapeutic Efficacy.
García-Bernal D, García-Arranz M, Yáñez RM, Hervás-Salcedo R, Cortés A, Fernández-García M, Hernando-Rodríguez M, Quintana-Bustamante Ó, Bueren JA, García-Olmo D, Moraleda JM, Segovia JC, Zapata AG. García-Bernal D, et al. Among authors: segovia jc. Front Cell Dev Biol. 2021 Mar 16;9:650664. doi: 10.3389/fcell.2021.650664. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33796536 Free PMC article. Review.
Generation of iPSCs from genetically corrected Brca2 hypomorphic cells: implications in cell reprogramming and stem cell therapy.
Navarro S, Moleiro V, Molina-Estevez FJ, Lozano ML, Chinchon R, Almarza E, Quintana-Bustamante O, Mostoslavsky G, Maetzig T, Galla M, Heinz N, Schiedlmeier B, Torres Y, Modlich U, Samper E, Río P, Segovia JC, Raya A, Güenechea G, Izpisua-Belmonte JC, Bueren JA. Navarro S, et al. Among authors: segovia jc. Stem Cells. 2014 Feb;32(2):436-46. doi: 10.1002/stem.1586. Stem Cells. 2014. PMID: 24420904
Gene Correction of iPSCs from a Wiskott-Aldrich Syndrome Patient Normalizes the Lymphoid Developmental and Functional Defects.
Laskowski TJ, Van Caeneghem Y, Pourebrahim R, Ma C, Ni Z, Garate Z, Crane AM, Li XS, Liao W, Gonzalez-Garay M, Segovia JC, Paschon DE, Rebar EJ, Holmes MC, Kaufman D, Vandekerckhove B, Davis BR. Laskowski TJ, et al. Among authors: segovia jc. Stem Cell Reports. 2016 Aug 9;7(2):139-48. doi: 10.1016/j.stemcr.2016.06.003. Epub 2016 Jul 7. Stem Cell Reports. 2016. PMID: 27396937 Free PMC article.
Gene Editing for Inherited Red Blood Cell Diseases.
Quintana-Bustamante O, Fañanas-Baquero S, Dessy-Rodriguez M, Ojeda-Pérez I, Segovia JC. Quintana-Bustamante O, et al. Among authors: segovia jc. Front Physiol. 2022 Mar 28;13:848261. doi: 10.3389/fphys.2022.848261. eCollection 2022. Front Physiol. 2022. PMID: 35418876 Free PMC article. Review.
Restored glyoxylate metabolism after AGXT gene correction and direct reprogramming of primary hyperoxaluria type 1 fibroblasts.
Nieto-Romero V, García-Torralba A, Molinos-Vicente A, Moya FJ, Rodríguez-Perales S, García-Escudero R, Salido E, Segovia JC, García-Bravo M. Nieto-Romero V, et al. Among authors: segovia jc. iScience. 2024 Mar 21;27(4):109530. doi: 10.1016/j.isci.2024.109530. eCollection 2024 Apr 19. iScience. 2024. PMID: 38577102 Free PMC article.
Constitutively active Akt induces ectodermal defects and impaired bone morphogenetic protein signaling.
Segrelles C, Moral M, Lorz C, Santos M, Lu J, Cascallana JL, Lara MF, Carbajal S, Martínez-Cruz AB, García-Escudero R, Beltran L, Segovia JC, Bravo A, DiGiovanni J, Paramio JM. Segrelles C, et al. Among authors: segovia jc. Mol Biol Cell. 2008 Jan;19(1):137-49. doi: 10.1091/mbc.e07-08-0764. Epub 2007 Oct 24. Mol Biol Cell. 2008. PMID: 17959825 Free PMC article.
117 results