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Extended Multicomponent Reactions with Indole Aldehydes: Access to Unprecedented Polyheterocyclic Scaffolds, Ligands of the Aryl Hydrocarbon Receptor.
Ghashghaei O, Pedrola M, Seghetti F, Martin VV, Zavarce R, Babiak M, Novacek J, Hartung F, Rolfes KM, Haarmann-Stemmann T, Lavilla R. Ghashghaei O, et al. Among authors: seghetti f. Angew Chem Int Ed Engl. 2021 Feb 1;60(5):2603-2608. doi: 10.1002/anie.202011253. Epub 2020 Nov 26. Angew Chem Int Ed Engl. 2021. PMID: 33048416
Prenylated Curcumin Analogues as Multipotent Tools To Tackle Alzheimer's Disease.
Bisceglia F, Seghetti F, Serra M, Zusso M, Gervasoni S, Verga L, Vistoli G, Lanni C, Catanzaro M, De Lorenzi E, Belluti F. Bisceglia F, et al. Among authors: seghetti f. ACS Chem Neurosci. 2019 Mar 20;10(3):1420-1433. doi: 10.1021/acschemneuro.8b00463. Epub 2019 Jan 2. ACS Chem Neurosci. 2019. PMID: 30556996 Free article.
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease.
Di Martino RMC, Pruccoli L, Bisi A, Gobbi S, Rampa A, Martinez A, Pérez C, Martinez-Gonzalez L, Paglione M, Di Schiavi E, Seghetti F, Tarozzi A, Belluti F. Di Martino RMC, et al. Among authors: seghetti f. ACS Chem Neurosci. 2020 Sep 2;11(17):2728-2740. doi: 10.1021/acschemneuro.0c00363. Epub 2020 Aug 3. ACS Chem Neurosci. 2020. PMID: 32663009 Free PMC article.
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold.
De Lorenzi E, Seghetti F, Tarozzi A, Pruccoli L, Contardi C, Serra M, Bisi A, Gobbi S, Vistoli G, Gervasoni S, Argentini C, Ghirardo G, Guarato G, Orso G, Belluti F, Di Martino RMC, Zusso M. De Lorenzi E, et al. Among authors: seghetti f. Eur J Med Chem. 2023 Apr 5;252:115297. doi: 10.1016/j.ejmech.2023.115297. Epub 2023 Mar 21. Eur J Med Chem. 2023. PMID: 36996713 Free article.
15 results