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Genome-Protective Topoisomerase 2a-Dependent G2 Arrest Requires p53 in hTERT-Positive Cancer Cells.
Cancer Res. 2022 May 3;82(9):1762-1773. doi: 10.1158/0008-5472.CAN-21-1785.
Cancer Res. 2022.
PMID: 35247890
Free PMC article.
A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest.
Deiss K, Lockwood N, Howell M, Segeren HA, Saunders RE, Chakravarty P, Soliman TN, Martini S, Rocha N, Semple R, Zalmas LP, Parker PJ.
Deiss K, et al. Among authors: segeren ha.
Nucleic Acids Res. 2019 Apr 8;47(6):2906-2921. doi: 10.1093/nar/gky1295.
Nucleic Acids Res. 2019.
PMID: 30590722
Free PMC article.
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Oncogenic RAS sensitizes cells to drug-induced replication stress via transcriptional silencing of P53.
Segeren HA, van Liere EA, Riemers FM, de Bruin A, Westendorp B.
Segeren HA, et al.
Oncogene. 2022 May;41(19):2719-2733. doi: 10.1038/s41388-022-02291-0. Epub 2022 Apr 7.
Oncogene. 2022.
PMID: 35393546
Free PMC article.
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Mechanisms used by cancer cells to tolerate drug-induced replication stress.
Segeren HA, Westendorp B.
Segeren HA, et al.
Cancer Lett. 2022 Sep 28;544:215804. doi: 10.1016/j.canlet.2022.215804. Epub 2022 Jun 22.
Cancer Lett. 2022.
PMID: 35750276
Free article.
Review.
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Feedback regulation between atypical E2Fs and APC/CCdh1 coordinates cell cycle progression.
Boekhout M, Yuan R, Wondergem AP, Segeren HA, van Liere EA, Awol N, Jansen I, Wolthuis RM, de Bruin A, Westendorp B.
Boekhout M, et al. Among authors: segeren ha.
EMBO Rep. 2016 Mar;17(3):414-27. doi: 10.15252/embr.201540984. Epub 2016 Feb 5.
EMBO Rep. 2016.
PMID: 26882548
Free PMC article.
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Cyclin F-dependent degradation of E2F7 is critical for DNA repair and G2-phase progression.
Yuan R, Liu Q, Segeren HA, Yuniati L, Guardavaccaro D, Lebbink RJ, Westendorp B, de Bruin A.
Yuan R, et al. Among authors: segeren ha.
EMBO J. 2019 Oct 15;38(20):e101430. doi: 10.15252/embj.2018101430. Epub 2019 Sep 2.
EMBO J. 2019.
PMID: 31475738
Free PMC article.
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Excessive E2F Transcription in Single Cancer Cells Precludes Transient Cell-Cycle Exit after DNA Damage.
Segeren HA, van Rijnberk LM, Moreno E, Riemers FM, van Liere EA, Yuan R, Wubbolts R, de Bruin A, Westendorp B.
Segeren HA, et al.
Cell Rep. 2020 Dec 1;33(9):108449. doi: 10.1016/j.celrep.2020.108449.
Cell Rep. 2020.
PMID: 33264622
Free article.
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Collection of cells for single-cell RNA sequencing using high-resolution fluorescence microscopy.
Segeren HA, Andree KC, Oomens L, Westendorp B.
Segeren HA, et al.
STAR Protoc. 2021 Aug 5;2(3):100718. doi: 10.1016/j.xpro.2021.100718. eCollection 2021 Sep 17.
STAR Protoc. 2021.
PMID: 34401784
Free PMC article.
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