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KIR2DS1 and KIR2DL1-C245 Dominantly Repress NK Cell Degranulation Triggered by Monoclonal or Bispecific Antibodies, whereas Education by Uptuning Inhibitory Killer Ig-related Receptors Exerts No Advantage in Ab-dependent Cellular Cytotoxicity.
J Immunol. 2024 Mar 1;212(5):868-880. doi: 10.4049/jimmunol.2300197.
J Immunol. 2024.
PMID: 38240527
Improved Leukemia Clearance After Adoptive Transfer of NK Cells Expressing the Bone Marrow Homing Receptor CXCR4R334X.
Segerberg F, Lambert M, Sanz-Ortega L, Andersson A, Childs RW, Carlsten M.
Segerberg F, et al.
Hemasphere. 2023 Nov 3;7(11):e974. doi: 10.1097/HS9.0000000000000974. eCollection 2023 Nov.
Hemasphere. 2023.
PMID: 37936677
Free PMC article.
No abstract available.
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Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells.
Palau A, Segerberg F, Lidschreiber M, Lidschreiber K, Naughton AJ, Needhamsen M, Jung LA, Jagodic M, Cramer P, Lehmann S, Carlsten M, Lennartsson A.
Palau A, et al. Among authors: segerberg f.
Leukemia. 2023 Sep;37(9):1830-1841. doi: 10.1038/s41375-023-01972-3. Epub 2023 Jul 26.
Leukemia. 2023.
PMID: 37495775
Free PMC article.
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LIR-1 educates expanded human NK cells and defines a unique antitumor NK cell subset with potent antibody-dependent cellular cytotoxicity.
Leijonhufvud C, Reger R, Segerberg F, Theorell J, Schlums H, Bryceson YT, Childs RW, Carlsten M.
Leijonhufvud C, et al. Among authors: segerberg f.
Clin Transl Immunology. 2021 Oct 5;10(10):e1346. doi: 10.1002/cti2.1346. eCollection 2021.
Clin Transl Immunology. 2021.
PMID: 34631057
Free PMC article.
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CRISPR/Cas9-Based Gene Engineering of Human Natural Killer Cells: Protocols for Knockout and Readouts to Evaluate Their Efficacy.
Lambert M, Leijonhufvud C, Segerberg F, Melenhorst JJ, Carlsten M.
Lambert M, et al. Among authors: segerberg f.
Methods Mol Biol. 2020;2121:213-239. doi: 10.1007/978-1-0716-0338-3_18.
Methods Mol Biol. 2020.
PMID: 32147798
Review.
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Autoantibodies to Killer Cell Immunoglobulin-Like Receptors in Patients With Systemic Lupus Erythematosus Induce Natural Killer Cell Hyporesponsiveness.
Segerberg F, Lundtoft C, Reid S, Hjorton K, Leonard D, Nordmark G, Carlsten M, Hagberg N.
Segerberg F, et al.
Front Immunol. 2019 Sep 11;10:2164. doi: 10.3389/fimmu.2019.02164. eCollection 2019.
Front Immunol. 2019.
PMID: 31572377
Free PMC article.
Clinical Trial.
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Enhanced Bone Marrow Homing of Natural Killer Cells Following mRNA Transfection With Gain-of-Function Variant CXCR4R334X.
Levy E, Reger R, Segerberg F, Lambert M, Leijonhufvud C, Baumer Y, Carlsten M, Childs R.
Levy E, et al. Among authors: segerberg f.
Front Immunol. 2019 Jun 5;10:1262. doi: 10.3389/fimmu.2019.01262. eCollection 2019.
Front Immunol. 2019.
PMID: 31231387
Free PMC article.
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