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Brain-muscle communication prevents muscle aging by maintaining daily physiology.
Kumar A, Vaca-Dempere M, Mortimer T, Deryagin O, Smith JG, Petrus P, Koronowski KB, Greco CM, Segalés J, Andrés E, Lukesova V, Zinna VM, Welz PS, Serrano AL, Perdiguero E, Sassone-Corsi P, Benitah SA, Muñoz-Cánoves P. Kumar A, et al. Among authors: segales j. Science. 2024 May 3;384(6695):563-572. doi: 10.1126/science.adj8533. Epub 2024 May 2. Science. 2024. PMID: 38696572
Multimodal cell atlas of the ageing human skeletal muscle.
Lai Y, Ramírez-Pardo I, Isern J, An J, Perdiguero E, Serrano AL, Li J, García-Domínguez E, Segalés J, Guo P, Lukesova V, Andrés E, Zuo J, Yuan Y, Liu C, Viña J, Doménech-Fernández J, Gómez-Cabrera MC, Song Y, Liu L, Xu X, Muñoz-Cánoves P, Esteban MA. Lai Y, et al. Among authors: segales j. Nature. 2024 May;629(8010):154-164. doi: 10.1038/s41586-024-07348-6. Epub 2024 Apr 22. Nature. 2024. PMID: 38649488 Free PMC article.
Gut-associated microbes are present and active in the pig nasal cavity.
Obregon-Gutierrez P, Bonillo-Lopez L, Correa-Fiz F, Sibila M, Segalés J, Kochanowski K, Aragon V. Obregon-Gutierrez P, et al. Among authors: segales j. Sci Rep. 2024 Apr 11;14(1):8470. doi: 10.1038/s41598-024-58681-9. Sci Rep. 2024. PMID: 38605046 Free PMC article.
Immunization with V987H-stabilized Spike glycoprotein protects K18-hACE2 mice and golden Syrian hamsters upon SARS-CoV-2 infection.
Ávila-Nieto C, Vergara-Alert J, Amengual-Rigo P, Ainsua-Enrich E, Brustolin M, Rodríguez de la Concepción ML, Pedreño-Lopez N, Rodon J, Urrea V, Pradenas E, Marfil S, Ballana E, Riveira-Muñoz E, Pérez M, Roca N, Tarrés-Freixas F, Cantero G, Pons-Grífols A, Rovirosa C, Aguilar-Gurrieri C, Ortiz R, Barajas A, Trinité B, Lepore R, Muñoz-Basagoiti J, Perez-Zsolt D, Izquierdo-Useros N, Valencia A, Blanco J, Guallar V, Clotet B, Segalés J, Carrillo J. Ávila-Nieto C, et al. Among authors: segales j. Nat Commun. 2024 Mar 21;15(1):2349. doi: 10.1038/s41467-024-46714-w. Nat Commun. 2024. PMID: 38514609 Free PMC article.
Plitidepsin as an Immunomodulator against Respiratory Viral Infections.
Losada A, Izquierdo-Useros N, Aviles P, Vergara-Alert J, Latino I, Segalés J, Gonzalez SF, Cuevas C, Raïch-Regué D, Muñoz-Alonso MJ, Perez-Zsolt D, Muñoz-Basagoiti J, Rodon J, Chang LA, Warang P, Singh G, Brustolin M, Cantero G, Roca N, Pérez M, Bustos-Morán E, White K, Schotsaert M, García-Sastre A. Losada A, et al. Among authors: segales j. J Immunol. 2024 Apr 15;212(8):1307-1318. doi: 10.4049/jimmunol.2300426. J Immunol. 2024. PMID: 38416036
Immunisation efficacy of a stabilised SARS-CoV-2 spike glycoprotein in two geriatric animal models.
Usai C, Ainsua-Enrich E, Gales VU, Pradenas E, Lorca-Oró C, Tarrés-Freixas F, Roca N, Pérez M, Ávila-Nieto C, Rodríguez de la Concepción ML, Pedreño-Lopez N, Carabelli J, Trinité B, Ballana E, Riveira-Muñoz E, Izquierdo-Useros N, Clotet B, Blanco J, Guallar V, Cantero G, Vergara-Alert J, Carrillo J, Segalés J. Usai C, et al. Among authors: segales j. NPJ Vaccines. 2024 Feb 27;9(1):48. doi: 10.1038/s41541-024-00840-0. NPJ Vaccines. 2024. PMID: 38413645 Free PMC article.
A monoclonal antibody targeting a large surface of the receptor binding motif shows pan-neutralizing SARS-CoV-2 activity.
de Campos-Mata L, Trinité B, Modrego A, Tejedor Vaquero S, Pradenas E, Pons-Grífols A, Rodrigo Melero N, Carlero D, Marfil S, Santiago C, Raïch-Regué D, Bueno-Carrasco MT, Tarrés-Freixas F, Abancó F, Urrea V, Izquierdo-Useros N, Riveira-Muñoz E, Ballana E, Pérez M, Vergara-Alert J, Segalés J, Carolis C, Arranz R, Blanco J, Magri G. de Campos-Mata L, et al. Among authors: segales j. Nat Commun. 2024 Feb 5;15(1):1051. doi: 10.1038/s41467-024-45171-9. Nat Commun. 2024. PMID: 38316751 Free PMC article.
Potential business model for a European vaccine R&D infrastructure and its estimated socio-economic impact.
Jungbluth S, Martin W, Slezak M, Depraetere H, Guzman CA, Ussi A, Morrow D, Van Heuverswyn F, Arnouts S, Carrondo MJT, Olesen O, Ottenhoff THM, Dockrell HM, Ho MM, Dobly A, Christensen D, Segalés J, Laurent F, Lantier F, Stockhofe-Zurwieden N, Morelli F, Langermans JAM, Verreck FAW, Le Grand R, Sloots A, Medaglini D, Lawrenz M, Collin N. Jungbluth S, et al. Among authors: segales j. F1000Res. 2023 Oct 24;12:1401. doi: 10.12688/f1000research.141399.1. eCollection 2023. F1000Res. 2023. PMID: 38298529 Free PMC article.
Exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the endangered Iberian lynx (Lynx pardinus).
Gómez JC, Cano-Terriza D, Segalés J, Vergara-Alert J, Zorrilla I, Del Rey T, Paniagua J, Gonzálvez M, Fernández-Bastit L, Nájera F, Montoya-Oliver JI, Salcedo J, García-Bocanegra I. Gómez JC, et al. Among authors: segales j. Vet Microbiol. 2024 Mar;290:110001. doi: 10.1016/j.vetmic.2024.110001. Epub 2024 Jan 17. Vet Microbiol. 2024. PMID: 38280305 Free article.
453 results