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Diploid hepatocytes drive physiological liver renewal in adult humans.
Heinke P, Rost F, Rode J, Trus P, Simonova I, Lázár E, Feddema J, Welsch T, Alkass K, Salehpour M, Zimmermann A, Seehofer D, Possnert G, Damm G, Druid H, Brusch L, Bergmann O. Heinke P, et al. Among authors: seehofer d. Cell Syst. 2022 Jun 15;13(6):499-507.e12. doi: 10.1016/j.cels.2022.05.001. Epub 2022 May 31. Cell Syst. 2022. PMID: 35649419 Free article.
Toxicogenomics directory of chemically exposed human hepatocytes.
Grinberg M, Stöber RM, Edlund K, Rempel E, Godoy P, Reif R, Widera A, Madjar K, Schmidt-Heck W, Marchan R, Sachinidis A, Spitkovsky D, Hescheler J, Carmo H, Arbo MD, van de Water B, Wink S, Vinken M, Rogiers V, Escher S, Hardy B, Mitic D, Myatt G, Waldmann T, Mardinoglu A, Damm G, Seehofer D, Nüssler A, Weiss TS, Oberemm A, Lampen A, Schaap MM, Luijten M, van Steeg H, Thasler WE, Kleinjans JC, Stierum RH, Leist M, Rahnenführer J, Hengstler JG. Grinberg M, et al. Among authors: seehofer d. Arch Toxicol. 2014 Dec;88(12):2261-87. doi: 10.1007/s00204-014-1400-x. Epub 2014 Nov 16. Arch Toxicol. 2014. PMID: 25399406
Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma.
Sajadian SO, Ehnert S, Vakilian H, Koutsouraki E, Damm G, Seehofer D, Thasler W, Dooley S, Baharvand H, Sipos B, Nussler AK. Sajadian SO, et al. Among authors: seehofer d. Clin Epigenetics. 2015 Sep 11;7(1):98. doi: 10.1186/s13148-015-0133-x. eCollection 2015. Clin Epigenetics. 2015. PMID: 26366235 Free PMC article.
Primary-like human hepatocytes genetically engineered to obtain proliferation competence display hepatic differentiation characteristics in monolayer and organotypical spheroid cultures.
Herzog N, Hansen M, Miethbauer S, Schmidtke KU, Anderer U, Lupp A, Sperling S, Seehofer D, Damm G, Scheibner K, Küpper JH. Herzog N, et al. Among authors: seehofer d. Cell Biol Int. 2016 Mar;40(3):341-53. doi: 10.1002/cbin.10574. Epub 2016 Jan 18. Cell Biol Int. 2016. PMID: 26715207
325 results