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Toxicogenomics directory of chemically exposed human hepatocytes.
Grinberg M, Stöber RM, Edlund K, Rempel E, Godoy P, Reif R, Widera A, Madjar K, Schmidt-Heck W, Marchan R, Sachinidis A, Spitkovsky D, Hescheler J, Carmo H, Arbo MD, van de Water B, Wink S, Vinken M, Rogiers V, Escher S, Hardy B, Mitic D, Myatt G, Waldmann T, Mardinoglu A, Damm G, Seehofer D, Nüssler A, Weiss TS, Oberemm A, Lampen A, Schaap MM, Luijten M, van Steeg H, Thasler WE, Kleinjans JC, Stierum RH, Leist M, Rahnenführer J, Hengstler JG. Grinberg M, et al. Among authors: seehofer d. Arch Toxicol. 2014 Dec;88(12):2261-87. doi: 10.1007/s00204-014-1400-x. Epub 2014 Nov 16. Arch Toxicol. 2014. PMID: 25399406
Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma.
Sajadian SO, Ehnert S, Vakilian H, Koutsouraki E, Damm G, Seehofer D, Thasler W, Dooley S, Baharvand H, Sipos B, Nussler AK. Sajadian SO, et al. Among authors: seehofer d. Clin Epigenetics. 2015 Sep 11;7(1):98. doi: 10.1186/s13148-015-0133-x. eCollection 2015. Clin Epigenetics. 2015. PMID: 26366235 Free PMC article.
Primary-like human hepatocytes genetically engineered to obtain proliferation competence display hepatic differentiation characteristics in monolayer and organotypical spheroid cultures.
Herzog N, Hansen M, Miethbauer S, Schmidtke KU, Anderer U, Lupp A, Sperling S, Seehofer D, Damm G, Scheibner K, Küpper JH. Herzog N, et al. Among authors: seehofer d. Cell Biol Int. 2016 Mar;40(3):341-53. doi: 10.1002/cbin.10574. Epub 2016 Jan 18. Cell Biol Int. 2016. PMID: 26715207
Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation.
Iwamoto N, D'Alessandro LA, Depner S, Hahn B, Kramer BA, Lucarelli P, Vlasov A, Stepath M, Böhm ME, Deharde D, Damm G, Seehofer D, Lehmann WD, Klingmüller U, Schilling M. Iwamoto N, et al. Among authors: d alessandro la, seehofer d. Sci Signal. 2016 Feb 2;9(413):ra13. doi: 10.1126/scisignal.aab1967. Sci Signal. 2016. PMID: 26838549
323 results