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Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.
Schappe MS, Szteyn K, Stremska ME, Mendu SK, Downs TK, Seegren PV, Mahoney MA, Dixit S, Krupa JK, Stipes EJ, Rogers JS, Adamson SE, Leitinger N, Desai BN. Schappe MS, et al. Among authors: seegren pv. Immunity. 2018 Jan 16;48(1):59-74.e5. doi: 10.1016/j.immuni.2017.11.026. Immunity. 2018. PMID: 29343440 Free PMC article.
Novel TRPM7 inhibitors with potent anti-inflammatory effects in vivo.
Busey GW, Manjegowda MC, Huang T, Iobst WH, Naphade SS, Kennedy JA, Doyle CA, Seegren PV, Lynch KR, Desai BN. Busey GW, et al. Among authors: seegren pv. bioRxiv [Preprint]. 2023 Aug 26:2023.05.22.541802. doi: 10.1101/2023.05.22.541802. bioRxiv. 2023. PMID: 37662207 Free PMC article. Preprint.