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Unique peptidic agonists of a juvenile hormone receptor with species-specific effects on insect development and reproduction.
Tumova S, Milacek M, Šnajdr I, Muthu M, Tuma R, Reha D, Jedlicka P, Bittova L, Novotna A, Majer P, Sedlak D, Jindra M. Tumova S, et al. Among authors: sedlak d. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2215541119. doi: 10.1073/pnas.2215541119. Epub 2022 Nov 21. Proc Natl Acad Sci U S A. 2022. PMID: 36409882 Free PMC article.
Structure-Activity Relationship of para-Carborane Selective Estrogen Receptor β Agonists.
Sedlák D, Wilson TA, Tjarks W, Radomska HS, Wang H, Kolla JN, Leśnikowski ZJ, Špičáková A, Ali T, Ishita K, Rakotondraibe LH, Vibhute S, Wang D, Anzenbacher P, Bennett C, Bartunek P, Coss CC. Sedlák D, et al. J Med Chem. 2021 Jul 8;64(13):9330-9353. doi: 10.1021/acs.jmedchem.1c00555. Epub 2021 Jun 28. J Med Chem. 2021. PMID: 34181409 Free article.
Crystallographic fragment screening-based study of a novel FAD-dependent oxidoreductase from Chaetomium thermophilum.
Švecová L, Østergaard LH, Skálová T, Schnorr KM, Koval' T, Kolenko P, Stránský J, Sedlák D, Dušková J, Trundová M, Hašek J, Dohnálek J. Švecová L, et al. Among authors: sedlak d. Acta Crystallogr D Struct Biol. 2021 Jun 1;77(Pt 6):755-775. doi: 10.1107/S2059798321003533. Epub 2021 May 14. Acta Crystallogr D Struct Biol. 2021. PMID: 34076590 Free PMC article.
Estradiol dimer inhibits tubulin polymerization and microtubule dynamics.
Jurášek M, Černohorská M, Řehulka J, Spiwok V, Sulimenko T, Dráberová E, Darmostuk M, Gurská S, Frydrych I, Buriánová R, Ruml T, Hajdúch M, Bartůněk P, Dráber P, Džubák P, Drašar PB, Sedlák D. Jurášek M, et al. Among authors: sedlak d. J Steroid Biochem Mol Biol. 2018 Oct;183:68-79. doi: 10.1016/j.jsbmb.2018.05.008. Epub 2018 May 24. J Steroid Biochem Mol Biol. 2018. PMID: 29803726
Lipophosphonoxins II: Design, Synthesis, and Properties of Novel Broad Spectrum Antibacterial Agents.
Seydlová G, Pohl R, Zborníková E, Ehn M, Šimák O, Panova N, Kolář M, Bogdanová K, Večeřová R, Fišer R, Šanderová H, Vítovská D, Sudzinová P, Pospíšil J, Benada O, Křížek T, Sedlák D, Bartůněk P, Krásný L, Rejman D. Seydlová G, et al. Among authors: sedlak d. J Med Chem. 2017 Jul 27;60(14):6098-6118. doi: 10.1021/acs.jmedchem.7b00355. Epub 2017 Jul 12. J Med Chem. 2017. PMID: 28654257
228 results