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LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation.
Simon M, Van Meter M, Ablaeva J, Ke Z, Gonzalez RS, Taguchi T, De Cecco M, Leonova KI, Kogan V, Helfand SL, Neretti N, Roichman A, Cohen HY, Meer MV, Gladyshev VN, Antoch MP, Gudkov AV, Sedivy JM, Seluanov A, Gorbunova V. Simon M, et al. Among authors: sedivy jm. Cell Metab. 2019 Apr 2;29(4):871-885.e5. doi: 10.1016/j.cmet.2019.02.014. Epub 2019 Mar 7. Cell Metab. 2019. PMID: 30853213 Free PMC article.
L1 drives IFN in senescent cells and promotes age-associated inflammation.
De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM. De Cecco M, et al. Among authors: sedivy jm. Nature. 2019 Feb;566(7742):73-78. doi: 10.1038/s41586-018-0784-9. Epub 2019 Feb 6. Nature. 2019. PMID: 30728521 Free PMC article.
Author Correction: L1 drives IFN in senescent cells and promotes age-associated inflammation.
De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM. De Cecco M, et al. Among authors: sedivy jm. Nature. 2019 Aug;572(7767):E5. doi: 10.1038/s41586-019-1350-9. Nature. 2019. PMID: 31296937 Free PMC article.
Sirt6 regulates lifespan in Drosophila melanogaster.
Taylor JR, Wood JG, Mizerak E, Hinthorn S, Liu J, Finn M, Gordon S, Zingas L, Chang C, Klein MA, Denu JM, Gorbunova V, Seluanov A, Boeke JD, Sedivy JM, Helfand SL. Taylor JR, et al. Among authors: sedivy jm. Proc Natl Acad Sci U S A. 2022 Feb 1;119(5):e2111176119. doi: 10.1073/pnas.2111176119. Proc Natl Acad Sci U S A. 2022. PMID: 35091469 Free PMC article.
Human Genomics. Sleeping dogs of the genome.
Gorbunova V, Boeke JD, Helfand SL, Sedivy JM. Gorbunova V, et al. Among authors: sedivy jm. Science. 2014 Dec 5;346(6214):1187-8. doi: 10.1126/science.aaa3177. Science. 2014. PMID: 25477445 Free PMC article. No abstract available.
Death by transposition - the enemy within?
Sedivy JM, Kreiling JA, Neretti N, De Cecco M, Criscione SW, Hofmann JW, Zhao X, Ito T, Peterson AL. Sedivy JM, et al. Bioessays. 2013 Dec;35(12):1035-43. doi: 10.1002/bies.201300097. Epub 2013 Oct 15. Bioessays. 2013. PMID: 24129940 Free PMC article.
166 results