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Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages.
Abuhammad A, Fullam E, Lowe ED, Staunton D, Kawamura A, Westwood IM, Bhakta S, Garner AC, Wilson DL, Seden PT, Davies SG, Russell AJ, Garman EF, Sim E. Abuhammad A, et al. Among authors: seden pt. PLoS One. 2012;7(12):e52790. doi: 10.1371/journal.pone.0052790. Epub 2012 Dec 28. PLoS One. 2012. PMID: 23285185 Free PMC article.
A novel color change mechanism for breast cancer biomarker detection: naphthoquinones as specific ligands of human arylamine N-acetyltransferase 1.
Laurieri N, Egleton JE, Varney A, Thinnes CC, Quevedo CE, Seden PT, Thompson S, Rodrigues-Lima F, Dairou J, Dupret JM, Russell AJ, Sim E. Laurieri N, et al. Among authors: seden pt. PLoS One. 2013 Aug 5;8(8):e70600. doi: 10.1371/journal.pone.0070600. Print 2013. PLoS One. 2013. PMID: 23940600 Free PMC article.
Structure-activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1.
Egleton JE, Thinnes CC, Seden PT, Laurieri N, Lee SP, Hadavizadeh KS, Measures AR, Jones AM, Thompson S, Varney A, Wynne GM, Ryan A, Sim E, Russell AJ. Egleton JE, et al. Among authors: seden pt. Bioorg Med Chem. 2014 Jun 1;22(11):3030-54. doi: 10.1016/j.bmc.2014.03.015. Epub 2014 Mar 28. Bioorg Med Chem. 2014. PMID: 24758871 Free article.
Stemistry: the control of stem cells in situ using chemistry.
Davies SG, Kennewell PD, Russell AJ, Seden PT, Westwood R, Wynne GM. Davies SG, et al. Among authors: seden pt. J Med Chem. 2015 Apr 9;58(7):2863-94. doi: 10.1021/jm500838d. Epub 2015 Jan 15. J Med Chem. 2015. PMID: 25590360 Review.