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Cardioprotection and lifespan extension by the natural polyamine spermidine.
Eisenberg T, Abdellatif M, Schroeder S, Primessnig U, Stekovic S, Pendl T, Harger A, Schipke J, Zimmermann A, Schmidt A, Tong M, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Magnes C, Trausinger G, Narath S, Meinitzer A, Hu Z, Kirsch A, Eller K, Carmona-Gutierrez D, Büttner S, Pietrocola F, Knittelfelder O, Schrepfer E, Rockenfeller P, Simonini C, Rahn A, Horsch M, Moreth K, Beckers J, Fuchs H, Gailus-Durner V, Neff F, Janik D, Rathkolb B, Rozman J, de Angelis MH, Moustafa T, Haemmerle G, Mayr M, Willeit P, von Frieling-Salewsky M, Pieske B, Scorrano L, Pieber T, Pechlaner R, Willeit J, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F. Eisenberg T, et al. Among authors: sedej s. Nat Med. 2016 Dec;22(12):1428-1438. doi: 10.1038/nm.4222. Epub 2016 Nov 14. Nat Med. 2016. PMID: 27841876 Free PMC article.
Spermidine supplementation and voluntary activity differentially affect obesity-related structural changes in the mouse lung.
Ahrendt N, Steingrüber T, Rajces A, Lopez-Rodriguez E, Eisenberg T, Magnes C, Madeo F, Sedej S, Schmiedl A, Ochs M, Mühlfeld C, Schipke J. Ahrendt N, et al. Among authors: sedej s. Am J Physiol Lung Cell Mol Physiol. 2020 Aug 1;319(2):L312-L324. doi: 10.1152/ajplung.00423.2019. Epub 2020 Jun 10. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32521164 Free article.
Loss of autophagy protein ATG5 impairs cardiac capacity in mice and humans through diminishing mitochondrial abundance and disrupting Ca2+ cycling.
Ljubojević-Holzer S, Kraler S, Djalinac N, Abdellatif M, Voglhuber J, Schipke J, Schmidt M, Kling KM, Franke GT, Herbst V, Zirlik A, von Lewinski D, Scherr D, Rainer PP, Kohlhaas M, Nickel A, Mühlfeld C, Maack C, Sedej S. Ljubojević-Holzer S, et al. Among authors: sedej s. Cardiovasc Res. 2022 May 6;118(6):1492-1505. doi: 10.1093/cvr/cvab112. Cardiovasc Res. 2022. PMID: 33752242 Free PMC article.
Autophagy in cardiovascular health and disease.
Abdellatif M, Ljubojevic-Holzer S, Madeo F, Sedej S. Abdellatif M, et al. Among authors: sedej s. Prog Mol Biol Transl Sci. 2020;172:87-106. doi: 10.1016/bs.pmbts.2020.04.022. Epub 2020 May 12. Prog Mol Biol Transl Sci. 2020. PMID: 32620252 Review.
Mass Spectrometry-Based Redox and Protein Profiling of Failing Human Hearts.
Tomin T, Schittmayer M, Sedej S, Bugger H, Gollmer J, Honeder S, Darnhofer B, Liesinger L, Zuckermann A, Rainer PP, Birner-Gruenberger R. Tomin T, et al. Among authors: sedej s. Int J Mol Sci. 2021 Feb 11;22(4):1787. doi: 10.3390/ijms22041787. Int J Mol Sci. 2021. PMID: 33670142 Free PMC article.
67 results