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Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules.
Qiu X, Mistry A, Ammirati MJ, Chrunyk BA, Clark RW, Cong Y, Culp JS, Danley DE, Freeman TB, Geoghegan KF, Griffor MC, Hawrylik SJ, Hayward CM, Hensley P, Hoth LR, Karam GA, Lira ME, Lloyd DB, McGrath KM, Stutzman-Engwall KJ, Subashi AK, Subashi TA, Thompson JF, Wang IK, Zhao H, Seddon AP. Qiu X, et al. Among authors: seddon ap. Nat Struct Mol Biol. 2007 Feb;14(2):106-13. doi: 10.1038/nsmb1197. Epub 2007 Jan 21. Nat Struct Mol Biol. 2007. PMID: 17237796
Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia.
Cunningham D, Danley DE, Geoghegan KF, Griffor MC, Hawkins JL, Subashi TA, Varghese AH, Ammirati MJ, Culp JS, Hoth LR, Mansour MN, McGrath KM, Seddon AP, Shenolikar S, Stutzman-Engwall KJ, Warren LC, Xia D, Qiu X. Cunningham D, et al. Among authors: seddon ap. Nat Struct Mol Biol. 2007 May;14(5):413-9. doi: 10.1038/nsmb1235. Epub 2007 Apr 15. Nat Struct Mol Biol. 2007. PMID: 17435765
Crystal structure of the herpes simplex virus 1 DNA polymerase.
Liu S, Knafels JD, Chang JS, Waszak GA, Baldwin ET, Deibel MR Jr, Thomsen DR, Homa FL, Wells PA, Tory MC, Poorman RA, Gao H, Qiu X, Seddon AP. Liu S, et al. Among authors: seddon ap. J Biol Chem. 2006 Jun 30;281(26):18193-200. doi: 10.1074/jbc.M602414200. Epub 2006 Apr 24. J Biol Chem. 2006. PMID: 16638752 Free article.
Flavins inhibit human cytomegalovirus UL80 protease via disulfide bond formation.
Baum EZ, Ding WD, Siegel MM, Hulmes J, Bebernitz GA, Sridharan L, Tabei K, Krishnamurthy G, Carofiglio T, Groves JT, Bloom JD, DiGrandi M, Bradley M, Ellestad G, Seddon AP, Gluzman Y. Baum EZ, et al. Among authors: seddon ap. Biochemistry. 1996 May 7;35(18):5847-55. doi: 10.1021/bi9529972. Biochemistry. 1996. PMID: 8639546
37 results