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The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss.
Secher A, Jelsing J, Baquero AF, Hecksher-Sørensen J, Cowley MA, Dalbøge LS, Hansen G, Grove KL, Pyke C, Raun K, Schäffer L, Tang-Christensen M, Verma S, Witgen BM, Vrang N, Bjerre Knudsen L. Secher A, et al. J Clin Invest. 2014 Oct;124(10):4473-88. doi: 10.1172/JCI75276. Epub 2014 Sep 9. J Clin Invest. 2014. PMID: 25202980 Free PMC article.
Semaglutide lowers body weight in rodents via distributed neural pathways.
Gabery S, Salinas CG, Paulsen SJ, Ahnfelt-Rønne J, Alanentalo T, Baquero AF, Buckley ST, Farkas E, Fekete C, Frederiksen KS, Helms HCC, Jeppesen JF, John LM, Pyke C, Nøhr J, Lu TT, Polex-Wolf J, Prevot V, Raun K, Simonsen L, Sun G, Szilvásy-Szabó A, Willenbrock H, Secher A, Knudsen LB, Hogendorf WFJ. Gabery S, et al. Among authors: secher a. JCI Insight. 2020 Mar 26;5(6):e133429. doi: 10.1172/jci.insight.133429. JCI Insight. 2020. PMID: 32213703 Free PMC article.
A genetic map of the mouse dorsal vagal complex and its role in obesity.
Ludwig MQ, Cheng W, Gordian D, Lee J, Paulsen SJ, Hansen SN, Egerod KL, Barkholt P, Rhodes CJ, Secher A, Knudsen LB, Pyke C, Myers MG Jr, Pers TH. Ludwig MQ, et al. Among authors: secher a. Nat Metab. 2021 Apr;3(4):530-545. doi: 10.1038/s42255-021-00363-1. Epub 2021 Mar 25. Nat Metab. 2021. PMID: 33767443
Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis.
Bakker W, Imbernon M, Salinas CG, Moro Chao DH, Hassouna R, Morel C, Martin C, Leger C, Denis RGP, Castel J, Peter A, Heni M, Maetzler W, Nielsen HS, Duquenne M, Schwaninger M, Lundh S, Johan Hogendorf WF, Gangarossa G, Secher A, Hecksher-Sørensen J, Pedersen TÅ, Prevot V, Luquet S. Bakker W, et al. Among authors: secher a. Cell Rep. 2022 Nov 22;41(8):111698. doi: 10.1016/j.celrep.2022.111698. Cell Rep. 2022. PMID: 36417883 Free PMC article.
Real-time trafficking and signaling of the glucagon-like peptide-1 receptor.
Roed SN, Wismann P, Underwood CR, Kulahin N, Iversen H, Cappelen KA, Schäffer L, Lehtonen J, Hecksher-Soerensen J, Secher A, Mathiesen JM, Bräuner-Osborne H, Whistler JL, Knudsen SM, Waldhoer M. Roed SN, et al. Among authors: secher a. Mol Cell Endocrinol. 2014 Feb 15;382(2):938-49. doi: 10.1016/j.mce.2013.11.010. Epub 2013 Nov 22. Mol Cell Endocrinol. 2014. PMID: 24275181 Free article.
78 results