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A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration.
Berrino E, Carradori S, Carta F, Melfi F, Gallorini M, Poli G, Tuccinardi T, Fernández-Bolaños JG, López Ó, Petzer JP, Petzer A, Guglielmi P, Secci D, Supuran CT. Berrino E, et al. Among authors: secci d. Antioxidants (Basel). 2023 Nov 25;12(12):2044. doi: 10.3390/antiox12122044. Antioxidants (Basel). 2023. PMID: 38136164 Free PMC article.
2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms.
Sequeira L, Distinto S, Meleddu R, Gaspari M, Angeli A, Cottiglia F, Secci D, Onali A, Sanna E, Borges F, Uriarte E, Alcaro S, Supuran CT, Maccioni E. Sequeira L, et al. Among authors: secci d. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2270183. doi: 10.1080/14756366.2023.2270183. Epub 2023 Oct 23. J Enzyme Inhib Med Chem. 2023. PMID: 37870190 Free PMC article.
Novel Insights on CAI-CORM Hybrids: Evaluation of the CO Releasing Properties and Pain-Relieving Activity of Differently Substituted Coumarins for the Treatment of Rheumatoid Arthritis.
Berrino E, Micheli L, Carradori S, di Cesare Mannelli L, Guglielmi P, De Luca A, Carta F, Ghelardini C, Secci D, Supuran CT. Berrino E, et al. Among authors: secci d. J Med Chem. 2023 Feb 9;66(3):1892-1908. doi: 10.1021/acs.jmedchem.2c01706. Epub 2023 Jan 26. J Med Chem. 2023. PMID: 36701258
Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa.
Cotman AE, Durcik M, Benedetto Tiz D, Fulgheri F, Secci D, Sterle M, Možina Š, Skok Ž, Zidar N, Zega A, Ilaš J, Peterlin Mašič L, Tomašič T, Hughes D, Huseby DL, Cao S, Garoff L, Berruga Fernández T, Giachou P, Crone L, Simoff I, Svensson R, Birnir B, Korol SV, Jin Z, Vicente F, Ramos MC, de la Cruz M, Glinghammar B, Lenhammar L, Henderson SR, Mundy JEA, Maxwell A, Stevenson CEM, Lawson DM, Janssen GV, Sterk GJ, Kikelj D. Cotman AE, et al. Among authors: secci d. J Med Chem. 2023 Jan 26;66(2):1380-1425. doi: 10.1021/acs.jmedchem.2c01597. Epub 2023 Jan 12. J Med Chem. 2023. PMID: 36634346 Free PMC article.
Novel Insights on Human Carbonic Anhydrase Inhibitors Based on Coumalic Acid: Design, Synthesis, Molecular Modeling Investigation, and Biological Studies.
Pontecorvi V, Mori M, Picarazzi F, Zara S, Carradori S, Cataldi A, Angeli A, Berrino E, Chimenti P, Ciogli A, Secci D, Guglielmi P, Supuran CT. Pontecorvi V, et al. Among authors: secci d. Int J Mol Sci. 2022 Jul 19;23(14):7950. doi: 10.3390/ijms23147950. Int J Mol Sci. 2022. PMID: 35887299 Free PMC article.
An innovative spectroscopic approach for qualitative and quantitative evaluation of Mb-CO from myoglobin carbonylation reaction through chemometrics methods.
Mansoldo FRP, Berrino E, Guglielmi P, Carradori S, Carta F, Secci D, Supuran CT, Vermelho AB. Mansoldo FRP, et al. Among authors: secci d. Spectrochim Acta A Mol Biomol Spectrosc. 2022 Feb 15;267(Pt 2):120602. doi: 10.1016/j.saa.2021.120602. Epub 2021 Nov 11. Spectrochim Acta A Mol Biomol Spectrosc. 2022. PMID: 34801390
Practical Synthesis and Application of Halogen-Doped Pyrrole Building Blocks.
Cotman AE, Guérin T, Kovačević I, Benedetto Tiz D, Durcik M, Fulgheri F, Možina Š, Secci D, Sterle M, Ilaš J, Zega A, Zidar N, Mašič LP, Tomašič T, Leroux FR, Hanquet G, Kikelj D. Cotman AE, et al. Among authors: secci d. ACS Omega. 2021 Mar 30;6(14):9723-9730. doi: 10.1021/acsomega.1c00331. eCollection 2021 Apr 13. ACS Omega. 2021. PMID: 33869952 Free PMC article.
116 results