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Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent.
Nalli M, Di Magno L, Wen Y, Liu X, D'Ambrosio M, Puxeddu M, Parisi A, Sebastiani J, Sorato A, Coluccia A, Ripa S, Di Pastena F, Capelli D, Montanari R, Masci D, Urbani A, Naro C, Sette C, Orlando V, D'Angelo S, Biagioni S, Bigogno C, Dondio G, Pastore A, Stornaiuolo M, Canettieri G, Liu T, Silvestri R, La Regina G. Nalli M, et al. Among authors: sebastiani j. ACS Pharmacol Transl Sci. 2023 Jul 3;6(7):1087-1103. doi: 10.1021/acsptsci.3c00092. eCollection 2023 Jul 14. ACS Pharmacol Transl Sci. 2023. PMID: 37470018 Free article.
Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia.
Puxeddu M, Shen H, Bai R, Coluccia A, Bufano M, Nalli M, Sebastiani J, Brancaccio D, Da Pozzo E, Tremolanti C, Martini C, Orlando V, Biagioni S, Sinicropi MS, Ceramella J, Iacopetta D, Coluccia AML, Hamel E, Liu T, Silvestri R, La Regina G. Puxeddu M, et al. Among authors: sebastiani j. Eur J Med Chem. 2021 Oct 5;221:113532. doi: 10.1016/j.ejmech.2021.113532. Epub 2021 May 5. Eur J Med Chem. 2021. PMID: 34052717
Discovery of a Novel Class of Norovirus Inhibitors with High Barrier of Resistance.
Van Dycke J, Puxeddu M, La Regina G, Mastrangelo E, Tarantino D, Rymenants J, Sebastiani J, Nalli M, Matthijnssens J, Neyts J, Silvestri R, Rocha-Pereira J. Van Dycke J, et al. Among authors: sebastiani j. Pharmaceuticals (Basel). 2021 Sep 30;14(10):1006. doi: 10.3390/ph14101006. Pharmaceuticals (Basel). 2021. PMID: 34681230 Free PMC article.
RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo.
Sebastiani J, Puxeddu M, Nalli M, Bai R, Altieri L, Rovella P, Gaudio E, Trisciuoglio D, Spriano F, Lavia P, Fionda C, Masci D, Urbani A, Bigogno C, Dondio G, Hamel E, Bertoni F, Silvestri R, La Regina G. Sebastiani J, et al. Eur J Med Chem. 2023 Jan 15;246:114997. doi: 10.1016/j.ejmech.2022.114997. Epub 2022 Dec 5. Eur J Med Chem. 2023. PMID: 36502578
Biological evaluation of [4-(4-aminophenyl)-1-(4-fluorophenyl)-1H-pyrrol-3-yl](3,4,5-trimethoxyphenyl)methanone as potential antineoplastic agent in 2D and 3D breast cancer models.
Mazzoccoli C, Crispo F, Laurenzana I, Pietrafesa M, Sisinni L, Lerose R, Telesca D, Milella MR, Liu T, Della Sala G, Sebastiani J, Silvestri R, La Regina G. Mazzoccoli C, et al. Among authors: sebastiani j. Arch Pharm (Weinheim). 2023 Oct;356(10):e2300354. doi: 10.1002/ardp.202300354. Epub 2023 Aug 21. Arch Pharm (Weinheim). 2023. PMID: 37603378
20 results