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Mitofusin-2 induced by exercise modifies lipid droplet-mitochondria communication, promoting fatty acid oxidation in male mice with NAFLD.
Bórquez JC, Díaz-Castro F, La Fuente FP, Espinoza K, Figueroa AM, Martínez-Ruíz I, Hernández V, López-Soldado I, Ventura R, Domingo JC, Bosch M, Fajardo A, Sebastián D, Espinosa A, Pol A, Zorzano A, Cortés V, Hernández-Alvarez MI, Troncoso R. Bórquez JC, et al. Among authors: sebastian d. Metabolism. 2024 Mar;152:155765. doi: 10.1016/j.metabol.2023.155765. Epub 2023 Dec 23. Metabolism. 2024. PMID: 38142958
Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis.
Sebastián D, Hernández-Alvarez MI, Segalés J, Sorianello E, Muñoz JP, Sala D, Waget A, Liesa M, Paz JC, Gopalacharyulu P, Orešič M, Pich S, Burcelin R, Palacín M, Zorzano A. Sebastián D, et al. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5523-8. doi: 10.1073/pnas.1108220109. Epub 2012 Mar 16. Proc Natl Acad Sci U S A. 2012. PMID: 22427360 Free PMC article.
Mfn2 modulates the UPR and mitochondrial function via repression of PERK.
Muñoz JP, Ivanova S, Sánchez-Wandelmer J, Martínez-Cristóbal P, Noguera E, Sancho A, Díaz-Ramos A, Hernández-Alvarez MI, Sebastián D, Mauvezin C, Palacín M, Zorzano A. Muñoz JP, et al. Among authors: sebastian d. EMBO J. 2013 Aug 28;32(17):2348-61. doi: 10.1038/emboj.2013.168. Epub 2013 Aug 6. EMBO J. 2013. PMID: 23921556 Free PMC article.
Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.
Schneeberger M, Dietrich MO, Sebastián D, Imbernón M, Castaño C, Garcia A, Esteban Y, Gonzalez-Franquesa A, Rodríguez IC, Bortolozzi A, Garcia-Roves PM, Gomis R, Nogueiras R, Horvath TL, Zorzano A, Claret M. Schneeberger M, et al. Among authors: sebastian d. Cell. 2013 Sep 26;155(1):172-87. doi: 10.1016/j.cell.2013.09.003. Cell. 2013. PMID: 24074867 Free PMC article.
Fatty acid transport protein 1 (FATP1) localizes in mitochondria in mouse skeletal muscle and regulates lipid and ketone body disposal.
Guitart M, Osorio-Conles O, Pentinat T, Cebrià J, García-Villoria J, Sala D, Sebastián D, Zorzano A, Ribes A, Jiménez-Chillarón JC, García-Martínez C, Gómez-Foix AM. Guitart M, et al. Among authors: sebastian d. PLoS One. 2014 May 23;9(5):e98109. doi: 10.1371/journal.pone.0098109. eCollection 2014. PLoS One. 2014. PMID: 24858472 Free PMC article.
150 results