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Multiomics characterization implicates PTK7 in ovarian cancer EMT and cell plasticity and offers strategies for therapeutic intervention.
Raivola J, Dini A, Karvonen H, Piki E, Salokas K, Niininen W, Kaleva L, Zhang K, Arjama M, Gudoityte G, Seashore-Ludlow B, Varjosalo M, Kallioniemi O, Hautaniemi S, Murumägi A, Ungureanu D. Raivola J, et al. Among authors: seashore ludlow b. Cell Death Dis. 2022 Aug 17;13(8):714. doi: 10.1038/s41419-022-05161-5. Cell Death Dis. 2022. PMID: 35977930 Free PMC article.
The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients.
Åkerlund E, Gudoityte G, Moussaud-Lamodière E, Lind O, Bwanika HC, Lehti K, Salehi S, Carlson J, Wallin E, Fernebro J, Östling P, Kallioniemi O, Joneborg U, Seashore-Ludlow B. Åkerlund E, et al. Among authors: seashore ludlow b. NPJ Precis Oncol. 2023 Oct 31;7(1):111. doi: 10.1038/s41698-023-00463-z. NPJ Precis Oncol. 2023. PMID: 37907613 Free PMC article.
MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia.
Sanjiv K, Calderón-Montaño JM, Pham TM, Erkers T, Tsuber V, Almlöf I, Höglund A, Heshmati Y, Seashore-Ludlow B, Nagesh Danda A, Gad H, Wiita E, Göktürk C, Rasti A, Friedrich S, Centio A, Estruch M, Våtsveen TK, Struyf N, Visnes T, Scobie M, Koolmeister T, Henriksson M, Wallner O, Sandvall T, Lehmann S, Theilgaard-Mönch K, Garnett MJ, Östling P, Walfridsson J, Helleday T, Warpman Berglund U. Sanjiv K, et al. Cancer Res. 2021 Nov 15;81(22):5733-5744. doi: 10.1158/0008-5472.CAN-21-0061. Epub 2021 Sep 30. Cancer Res. 2021. PMID: 34593524 Free PMC article.
The transcriptome-wide landscape of molecular subtype-specific mRNA expression profiles in acute myeloid leukemia.
Mou T, Pawitan Y, Stahl M, Vesterlund M, Deng W, Jafari R, Bohlin A, Österroos A, Siavelis L, Bäckvall H, Erkers T, Kiviluoto S, Seashore-Ludlow B, Östling P, Orre LM, Kallioniemi O, Lehmann S, Lehtiö J, Vu TN. Mou T, et al. Am J Hematol. 2021 May 1;96(5):580-588. doi: 10.1002/ajh.26141. Epub 2021 Mar 10. Am J Hematol. 2021. PMID: 33625756 Free article.
Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors.
Oberlick EM, Rees MG, Seashore-Ludlow B, Vazquez F, Nelson GM, Dharia NV, Weir BA, Tsherniak A, Ghandi M, Krill-Burger JM, Meyers RM, Wang X, Montgomery P, Root DE, Bieber JM, Radko S, Cheah JH, Hon CS, Shamji AF, Clemons PA, Park PJ, Dyer MA, Golub TR, Stegmaier K, Hahn WC, Stewart EA, Schreiber SL, Roberts CWM. Oberlick EM, et al. Cell Rep. 2019 Aug 27;28(9):2331-2344.e8. doi: 10.1016/j.celrep.2019.07.021. Cell Rep. 2019. PMID: 31461650 Free PMC article.
Miniaturized and multiplexed high-content screening of drug and immune sensitivity in a multichambered microwell chip.
Sandström N, Carannante V, Olofsson K, Sandoz PA, Moussaud-Lamodière EL, Seashore-Ludlow B, Van Ooijen H, Verron Q, Frisk T, Takai M, Wiklund M, Östling P, Önfelt B. Sandström N, et al. Cell Rep Methods. 2022 Jul 18;2(7):100256. doi: 10.1016/j.crmeth.2022.100256. eCollection 2022 Jul 18. Cell Rep Methods. 2022. PMID: 35880015 Free PMC article.
49 results