Sears RC - Search Results

1

MYC Deregulation and PTEN Loss Model Tumor and Stromal Heterogeneity of Aggressive Triple-Negative Breast Cancer.

Doha ZO, Wang X, Calistri NL, Eng J, Daniel CJ, Ternes L, Kim EN, Pelz C, Munks M, Betts C, Kwon S, Bucher E, Li X, Waugh T, Tatarova Z, Blumberg D, Ko A, Kirchberger N, Pietenpol JA, Sanders ME, Langer EM, Dai MS, Mills G, Chin K, Chang YH, Coussens LM, Gray JW, Heiser LM, Sears RC. Doha ZO, et al. Among authors: sears rc. Nat Commun. 2023 Sep 13;14(1):5665. doi: 10.1038/s41467-023-40841-6. Nat Commun. 2023. PMID: 37704631 Free PMC article.

2

Melanocyte and keratinocyte carcinogenesis: p53 family protein activities and intersecting mRNA expression profiles.

Kulesz-Martin M, Lagowski J, Fei S, Pelz C, Sears R, Powell MB, Halaban R, Johnson J. Kulesz-Martin M, et al. J Investig Dermatol Symp Proc. 2005 Nov;10(2):142-52. doi: 10.1111/j.1087-0024.2005.200405.x. J Investig Dermatol Symp Proc. 2005. PMID: 16363065 Free article. Review.

3

Inhibition of c-Myc activity by ribosomal protein L11.

Dai MS, Arnold H, Sun XX, Sears R, Lu H. Dai MS, et al. EMBO J. 2007 Jul 25;26(14):3332-45. doi: 10.1038/sj.emboj.7601776. Epub 2007 Jun 28. EMBO J. 2007. PMID: 17599065 Free PMC article.

4

Feedback regulation of c-Myc by ribosomal protein L11.

Dai MS, Sears R, Lu H. Dai MS, et al. Cell Cycle. 2007 Nov 15;6(22):2735-41. doi: 10.4161/cc.6.22.4895. Epub 2007 Aug 14. Cell Cycle. 2007. PMID: 18032916 Free PMC article. Review.

5

Global rank-invariant set normalization (GRSN) to reduce systematic distortions in microarray data.

Pelz CR, Kulesz-Martin M, Bagby G, Sears RC. Pelz CR, et al. Among authors: sears rc. BMC Bioinformatics. 2008 Dec 4;9:520. doi: 10.1186/1471-2105-9-520. BMC Bioinformatics. 2008. PMID: 19055840 Free PMC article.

6

The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc.

Arnold HK, Zhang X, Daniel CJ, Tibbitts D, Escamilla-Powers J, Farrell A, Tokarz S, Morgan C, Sears RC. Arnold HK, et al. Among authors: sears rc. EMBO J. 2009 Mar 4;28(5):500-12. doi: 10.1038/emboj.2008.279. Epub 2009 Jan 8. EMBO J. 2009. PMID: 19131971 Free PMC article.

7

The tumor suppressor protein HBP1 is a novel c-myc-binding protein that negatively regulates c-myc transcriptional activity.

Escamilla-Powers JR, Daniel CJ, Farrell A, Taylor K, Zhang X, Byers S, Sears R. Escamilla-Powers JR, et al. J Biol Chem. 2010 Feb 12;285(7):4847-58. doi: 10.1074/jbc.M109.074856. Epub 2009 Dec 11. J Biol Chem. 2010. PMID: 20008325 Free PMC article.

8

Phosphorylation regulates c-Myc's oncogenic activity in the mammary gland.

Wang X, Cunningham M, Zhang X, Tokarz S, Laraway B, Troxell M, Sears RC. Wang X, et al. Among authors: sears rc. Cancer Res. 2011 Feb 1;71(3):925-36. doi: 10.1158/0008-5472.CAN-10-1032. Epub 2011 Jan 25. Cancer Res. 2011. PMID: 21266350 Free PMC article.

9

Ribosomal protein L11 recruits miR-24/miRISC to repress c-Myc expression in response to ribosomal stress.

Challagundla KB, Sun XX, Zhang X, DeVine T, Zhang Q, Sears RC, Dai MS. Challagundla KB, et al. Among authors: sears rc. Mol Cell Biol. 2011 Oct;31(19):4007-21. doi: 10.1128/MCB.05810-11. Epub 2011 Aug 1. Mol Cell Biol. 2011. PMID: 21807902 Free PMC article.

10

Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression.

Zhang X, Farrell AS, Daniel CJ, Arnold H, Scanlan C, Laraway BJ, Janghorban M, Lum L, Chen D, Troxell M, Sears R. Zhang X, et al. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2790-5. doi: 10.1073/pnas.1100764108. Epub 2011 Aug 1. Proc Natl Acad Sci U S A. 2012. PMID: 21808024 Free PMC article.

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