Sears JD - Search Results

1

Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.

Merten EM, Sears JD, Leisner TM, Hardy PB, Ghoshal A, Hossain MA, Asressu KH, Brown PJ, Stashko MA, Herring LE, Mordant AL, Webb TS, Mills CA, Barker NK, Arnold JJ, Cameron CE, Streblow DN, Moorman NJ, Heise M, Willson TM, Popov KI, Pearce KH. Merten EM, et al. Among authors: sears jd. bioRxiv [Preprint]. 2024 Mar 22:2024.03.22.586341. doi: 10.1101/2024.03.22.586341. bioRxiv. 2024. PMID: 38562906 Free PMC article. Preprint.

2

Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice.

Wells AE, Wilson JJ, Heuer SE, Sears JD, Wei J, Pandey R, Costa MW, Kaczorowski CC, Roopenian DC, Chang CH, Carter GW. Wells AE, et al. Among authors: sears jd. PLoS One. 2024 Mar 7;19(3):e0299595. doi: 10.1371/journal.pone.0299595. eCollection 2024. PLoS One. 2024. PMID: 38451972 Free PMC article.

3

The genetic basis of novel trait gain in walking fish.

Herbert AL, Allard CA, McCoy MJ, Wucherpfennig JI, Krueger SP, Chen HI, Gourlay AN, Jackson KD, Abbo LA, Bennett SH, Sears JD, Rhyne AL, Bellono NW, Kingsley DM. Herbert AL, et al. Among authors: sears jd. bioRxiv [Preprint]. 2023 Oct 14:2023.10.14.562356. doi: 10.1101/2023.10.14.562356. bioRxiv. 2023. PMID: 37873105 Free PMC article. Preprint.

4

Glucose oxidation-dependent survival of activated B cells provides a putative novel therapeutic target for lupus treatment.

Wilson JJ, Wei J, Daamen AR, Sears JD, Bechtel E, Mayberry CL, Stafford GA, Bechtold L, Grammer AC, Lipsky PE, Roopenian DC, Chang CH. Wilson JJ, et al. Among authors: sears jd. iScience. 2023 Jul 27;26(9):107487. doi: 10.1016/j.isci.2023.107487. eCollection 2023 Sep 15. iScience. 2023. PMID: 37636066 Free PMC article.

5

Transcriptome Analysis Reveals Organ-Specific Effects of 2-Deoxyglucose Treatment in Healthy Mice.

Wells AE, Wilson JJ, Sears JD, Wei J, Heuer S, Pandey R, Costa MW, Kaczorowski CC, Roopenian DC, Chang CH, Carter GW. Wells AE, et al. Among authors: sears jd. bioRxiv [Preprint]. 2023 May 12:2023.04.24.537717. doi: 10.1101/2023.04.24.537717. bioRxiv. 2023. PMID: 37162857 Free PMC article. Updated. Preprint.

6

Smoking and Radiation-induced Skin Injury: Analysis of a Multiracial, Multiethnic Prospective Clinical Trial.

Hughes RT, Ip EH, Urbanic JJ, Hu JJ, Weaver KE, Lively MO, Winkfield KM, Shaw EG, Diaz LB, Brown DR, Strasser J, Sears JD, Lesser GJ. Hughes RT, et al. Among authors: sears jd. Clin Breast Cancer. 2022 Dec;22(8):762-770. doi: 10.1016/j.clbc.2022.09.003. Epub 2022 Sep 16. Clin Breast Cancer. 2022. PMID: 36216768 Free PMC article.

7

Side-on coordination of diphosphorus to a mononuclear iron center.

Wang S, Sears JD, Moore CE, Rheingold AL, Neidig ML, Figueroa JS. Wang S, et al. Among authors: sears jd. Science. 2022 Mar 25;375(6587):1393-1397. doi: 10.1126/science.abn7100. Epub 2022 Mar 24. Science. 2022. PMID: 35324298 Free PMC article.

8

A TMEDA-Iron Adduct Reaction Manifold in Iron-Catalyzed C(sp² )-C(sp³ ) Cross-Coupling Reactions.

Bakas NJ, Sears JD, Brennessel WW, Neidig ML. Bakas NJ, et al. Among authors: sears jd. Angew Chem Int Ed Engl. 2022 Apr 4;61(15):e202114986. doi: 10.1002/anie.202114986. Epub 2022 Feb 18. Angew Chem Int Ed Engl. 2022. PMID: 35104376 Free PMC article.

9

Targeting metabolism to reverse T-cell exhaustion in chronic viral infections.

Sears JD, Waldron KJ, Wei J, Chang CH. Sears JD, et al. Immunology. 2021 Feb;162(2):135-144. doi: 10.1111/imm.13238. Epub 2020 Aug 11. Immunology. 2021. PMID: 32681647 Free PMC article. Review.

10

The Exceptional Diversity of Homoleptic Uranium-Methyl Complexes.

Sears JD, Sergentu DC, Baker TM, Brennessel WW, Autschbach J, Neidig ML. Sears JD, et al. Angew Chem Int Ed Engl. 2020 Aug 3;59(32):13586-13590. doi: 10.1002/anie.202005138. Epub 2020 Jun 4. Angew Chem Int Ed Engl. 2020. PMID: 32392392

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