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Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.
Williams BL, Zouache MA, Seager NA, Pappas CM, Liu J, Anstadt RA, Hubbard WC, Thomas J, Hageman JL, Mohler J, Richards BT, Hageman GS. Williams BL, et al. Among authors: seager na. Invest Ophthalmol Vis Sci. 2024 Apr 1;65(4):34. doi: 10.1167/iovs.65.4.34. Invest Ophthalmol Vis Sci. 2024. PMID: 38648039 Free PMC article.
Levels of complement factor H-related 4 protein do not influence susceptibility to age-related macular degeneration or its course of progression.
Zouache MA, Richards BT, Pappas CM, Anstadt RA, Liu J, Corsetti T, Matthews S, Seager NA, Schmitz-Valckenberg S, Fleckenstein M, Hubbard WC, Thomas J, Hageman JL, Williams BL, Hageman GS. Zouache MA, et al. Among authors: seager na. Nat Commun. 2024 Jan 10;15(1):443. doi: 10.1038/s41467-023-44605-0. Nat Commun. 2024. PMID: 38200010 Free PMC article.
Chromosome 10q26-driven age-related macular degeneration is associated with reduced levels of HTRA1 in human retinal pigment epithelium.
Williams BL, Seager NA, Gardiner JD, Pappas CM, Cronin MC, Amat di San Filippo C, Anstadt RA, Liu J, Toso MA, Nichols L, Parnell TJ, Eve JR, Heinz S, Hayes MGB, Bartel PL, Zouache MA, Richards BT, Hageman GS. Williams BL, et al. Among authors: seager na. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2103617118. doi: 10.1073/pnas.2103617118. Proc Natl Acad Sci U S A. 2021. PMID: 34301870 Free PMC article.