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A Phase I study of the angiogenesis inhibitor SU5416 (semaxanib) in solid tumours, incorporating dynamic contrast MR pharmacodynamic end points.
O'Donnell A, Padhani A, Hayes C, Kakkar AJ, Leach M, Trigo JM, Scurr M, Raynaud F, Phillips S, Aherne W, Hardcastle A, Workman P, Hannah A, Judson I. O'Donnell A, et al. Among authors: scurr m. Br J Cancer. 2005 Oct 17;93(8):876-83. doi: 10.1038/sj.bjc.6602797. Br J Cancer. 2005. PMID: 16222321 Free PMC article. Clinical Trial.
Sarcoma.
Scurr M, Judson I. Scurr M, et al. Cancer Chemother Biol Response Modif. 2003;21:637-53. doi: 10.1016/s0921-4410(03)21030-9. Cancer Chemother Biol Response Modif. 2003. PMID: 15338767 Review. No abstract available.
Soft-tissue and bone sarcomas.
Scurr M, Judson I. Scurr M, et al. Cancer Chemother Biol Response Modif. 2005;22:591-604. doi: 10.1016/s0921-4410(04)22026-9. Cancer Chemother Biol Response Modif. 2005. PMID: 16110630 Review. No abstract available.
Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study.
Olmos D, Postel-Vinay S, Molife LR, Okuno SH, Schuetze SM, Paccagnella ML, Batzel GN, Yin D, Pritchard-Jones K, Judson I, Worden FP, Gualberto A, Scurr M, de Bono JS, Haluska P. Olmos D, et al. Among authors: scurr m. Lancet Oncol. 2010 Feb;11(2):129-35. doi: 10.1016/S1470-2045(09)70354-7. Epub 2009 Dec 23. Lancet Oncol. 2010. PMID: 20036194 Free PMC article. Clinical Trial.
Role of palliative chemotherapy in advanced epithelioid sarcoma.
Jones RL, Constantinidou A, Olmos D, Thway K, Fisher C, Al-Muderis O, Scurr M, Judson IR. Jones RL, et al. Among authors: scurr m. Am J Clin Oncol. 2012 Aug;35(4):351-7. doi: 10.1097/COC.0b013e3182118cf7. Am J Clin Oncol. 2012. PMID: 21422990
Phase I and pharmacokinetic study of XR11576, an oral topoisomerase I and II inhibitor, administered on days 1-5 of a 3-weekly cycle in patients with advanced solid tumours.
de Jonge MJ, Kaye S, Verweij J, Brock C, Reade S, Scurr M, van Doorn L, Verheij C, Loos W, Brindley C, Mistry P, Cooper M, Judson I. de Jonge MJ, et al. Among authors: scurr m. Br J Cancer. 2004 Oct 18;91(8):1459-65. doi: 10.1038/sj.bjc.6602178. Br J Cancer. 2004. PMID: 15452551 Free PMC article. Clinical Trial.
69 results