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Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis.
Neopane K, Kozlov N, Negoita F, Murray-Segal L, Brink R, Hoque A, Ovens AJ, Tjin G, McAloon LM, Yu D, Ling NXY, Sanders MJ, Oakhill JS, Scott JW, Steinberg GR, Loh K, Kemp BE, Sakamoto K, Galic S. Neopane K, et al. Among authors: scott jw. Cell Rep. 2022 Dec 20;41(12):111862. doi: 10.1016/j.celrep.2022.111862. Cell Rep. 2022. PMID: 36543129 Free article.
AMPK structure and regulation from three angles.
Kemp BE, Oakhill JS, Scott JW. Kemp BE, et al. Among authors: scott jw. Structure. 2007 Oct;15(10):1161-3. doi: 10.1016/j.str.2007.09.006. Structure. 2007. PMID: 17937905 Free article. No abstract available.
Structure and function of AMP-activated protein kinase.
Oakhill JS, Scott JW, Kemp BE. Oakhill JS, et al. Among authors: scott jw. Acta Physiol (Oxf). 2009 May;196(1):3-14. doi: 10.1111/j.1748-1716.2009.01977.x. Epub 2009 Feb 20. Acta Physiol (Oxf). 2009. PMID: 19245650 Review.
AMPK/SNF1 structure: a menage a trois of energy-sensing.
Scott JW, Oakhill JS, van Denderen BJ. Scott JW, et al. Front Biosci (Landmark Ed). 2009 Jan 1;14(2):596-610. doi: 10.2741/3266. Front Biosci (Landmark Ed). 2009. PMID: 19273088 Free article. Review.
Whole body deletion of AMP-activated protein kinase {beta}2 reduces muscle AMPK activity and exercise capacity.
Steinberg GR, O'Neill HM, Dzamko NL, Galic S, Naim T, Koopman R, Jørgensen SB, Honeyman J, Hewitt K, Chen ZP, Schertzer JD, Scott JW, Koentgen F, Lynch GS, Watt MJ, van Denderen BJ, Campbell DJ, Kemp BE. Steinberg GR, et al. Among authors: scott jw. J Biol Chem. 2010 Nov 26;285(48):37198-209. doi: 10.1074/jbc.M110.102434. Epub 2010 Sep 20. J Biol Chem. 2010. PMID: 20855892 Free PMC article.
AMPK is a direct adenylate charge-regulated protein kinase.
Oakhill JS, Steel R, Chen ZP, Scott JW, Ling N, Tam S, Kemp BE. Oakhill JS, et al. Among authors: scott jw. Science. 2011 Jun 17;332(6036):1433-5. doi: 10.1126/science.1200094. Science. 2011. PMID: 21680840
501 results