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Dual blockade of IL-4 and IL-13 with dupilumab, an IL-4Rα antibody, is required to broadly inhibit type 2 inflammation.
Le Floc'h A, Allinne J, Nagashima K, Scott G, Birchard D, Asrat S, Bai Y, Lim WK, Martin J, Huang T, Potocky TB, Kim JH, Rafique A, Papadopoulos NJ, Stahl N, Yancopoulos GD, Murphy AJ, Sleeman MA, Orengo JM. Le Floc'h A, et al. Among authors: scott g. Allergy. 2020 May;75(5):1188-1204. doi: 10.1111/all.14151. Epub 2020 Jan 3. Allergy. 2020. PMID: 31838750 Free PMC article.
IL-33 blockade affects mediators of persistence and exacerbation in a model of chronic airway inflammation.
Allinne J, Scott G, Lim WK, Birchard D, Erjefält JS, Sandén C, Ben LH, Agrawal A, Kaur N, Kim JH, Kamat V, Fury W, Huang T, Stahl N, Yancopoulos GD, Murphy AJ, Sleeman MA, Orengo JM. Allinne J, et al. Among authors: scott g. J Allergy Clin Immunol. 2019 Dec;144(6):1624-1637.e10. doi: 10.1016/j.jaci.2019.08.039. Epub 2019 Sep 25. J Allergy Clin Immunol. 2019. PMID: 31562870 Free article.
Blocking common γ chain cytokine signaling ameliorates T cell-mediated pathogenesis in disease models.
Le Floc'h A, Nagashima K, Birchard D, Scott G, Ben LH, Ajithdoss D, Gayvert K, Romero Hernandez A, Herbin O, Tay A, Farrales P, Korgaonkar CK, Pan H, Shah S, Kamat V, Chatterjee I, Popke J, Oyejide A, Lim WK, Kim JH, Huang T, Franklin M, Olson W, Norton T, Perlee L, Yancopoulos GD, Murphy AJ, Sleeman MA, Orengo JM. Le Floc'h A, et al. Among authors: scott g. Sci Transl Med. 2023 Jan 11;15(678):eabo0205. doi: 10.1126/scitranslmed.abo0205. Epub 2023 Jan 11. Sci Transl Med. 2023. PMID: 36630481
Differentiating Prodromal Dementia with Lewy Bodies from Prodromal Alzheimer's Disease: A Pragmatic Review for Clinicians.
Wyman-Chick KA, Chaudhury P, Bayram E, Abdelnour C, Matar E, Chiu SY, Ferreira D, Hamilton CA, Donaghy PC, Rodriguez-Porcel F, Toledo JB, Habich A, Barrett MJ, Patel B, Jaramillo-Jimenez A, Scott GD, Kane JPM. Wyman-Chick KA, et al. Among authors: scott gd. Neurol Ther. 2024 May 8. doi: 10.1007/s40120-024-00620-x. Online ahead of print. Neurol Ther. 2024. PMID: 38720013 Free article.
Persistent GDNF Expression 45 Months after Putaminal Infusion of AAV2-GDNF in a Patient with Parkinson's Disease.
Heiss JD, Ray-Chaudhury A, Kleiner DE, Ehrlich DJ, Scott G, Edwards NA, Goldstein DS, Hammoud DA, Hadaczek P, Van Laar VS, Graff SA, Herscovitch P, Lungu C, Hallett M, Lonser RR, Zaghloul KA, Bankiewicz KS. Heiss JD, et al. Among authors: scott g. Mov Disord. 2024 May 8. doi: 10.1002/mds.29820. Online ahead of print. Mov Disord. 2024. PMID: 38718138
2,826 results