Scott D - Search Results

1

Molecular insights into an ancient form of Paget's disease of bone.

Shaw B, Burrell CL, Green D, Navarro-Martinez A, Scott D, Daroszewska A, van 't Hof R, Smith L, Hargrave F, Mistry S, Bottrill A, Kessler BM, Fischer R, Singh A, Dalmay T, Fraser WD, Henneberger K, King T, Gonzalez S, Layfield R. Shaw B, et al. Among authors: scott d. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10463-10472. doi: 10.1073/pnas.1820556116. Epub 2019 Apr 29. Proc Natl Acad Sci U S A. 2019. PMID: 31036632 Free PMC article.

2

Second-harmonic generation imaging of collagen in ancient bone.

Thomas B, McIntosh D, Fildes T, Smith L, Hargrave F, Islam M, Thompson T, Layfield R, Scott D, Shaw B, Burrell CL, Gonzalez S, Taylor S. Thomas B, et al. Among authors: scott d. Bone Rep. 2017 Nov 1;7:137-144. doi: 10.1016/j.bonr.2017.10.005. eCollection 2017 Dec. Bone Rep. 2017. PMID: 29124084 Free PMC article.

3

Structural insights into interactions between ubiquitin specific protease 5 and its polyubiquitin substrates by mass spectrometry and ion mobility spectrometry.

Scott D, Layfield R, Oldham NJ. Scott D, et al. Protein Sci. 2015 Aug;24(8):1257-63. doi: 10.1002/pro.2692. Epub 2015 May 29. Protein Sci. 2015. PMID: 25970461 Free PMC article.

4

Ion mobility-mass spectrometry reveals conformational flexibility in the deubiquitinating enzyme USP5.

Scott D, Layfield R, Oldham NJ. Scott D, et al. Proteomics. 2015 Aug;15(16):2835-41. doi: 10.1002/pmic.201400457. Epub 2015 Mar 9. Proteomics. 2015. PMID: 25641936

5

Mass spectrometry insights into a tandem ubiquitin-binding domain hybrid engineered for the selective recognition of unanchored polyubiquitin.

Scott D, Garner TP, Long J, Strachan J, Mistry SC, Bottrill AR, Tooth DJ, Searle MS, Oldham NJ, Layfield R. Scott D, et al. Proteomics. 2016 Jul;16(14):1961-9. doi: 10.1002/pmic.201600067. Proteomics. 2016. PMID: 27037516

6

Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD.

Goode A, Butler K, Long J, Cavey J, Scott D, Shaw B, Sollenberger J, Gell C, Johansen T, Oldham NJ, Searle MS, Layfield R. Goode A, et al. Among authors: scott d. Autophagy. 2016 Jul 2;12(7):1094-104. doi: 10.1080/15548627.2016.1170257. Epub 2016 May 9. Autophagy. 2016. PMID: 27158844 Free PMC article.

7

An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity toward the autophagy-related hATG8 proteins.

Brennan A, Layfield R, Long J, Williams HEL, Oldham NJ, Scott D, Searle MS. Brennan A, et al. Among authors: scott d. J Biol Chem. 2022 Feb;298(2):101514. doi: 10.1016/j.jbc.2021.101514. Epub 2021 Dec 18. J Biol Chem. 2022. PMID: 34929165 Free PMC article.

8

Ubiquitin-binding domains: mechanisms of ubiquitin recognition and use as tools to investigate ubiquitin-modified proteomes.

Scott D, Oldham NJ, Strachan J, Searle MS, Layfield R. Scott D, et al. Proteomics. 2015 Mar;15(5-6):844-61. doi: 10.1002/pmic.201400341. Epub 2014 Dec 28. Proteomics. 2015. PMID: 25327553 Review.

9

An FTLD-associated SQSTM1 variant impacts Nrf2 and NF-κB signalling and is associated with reduced phosphorylation of p62.

Foster A, Scott D, Layfield R, Rea SL. Foster A, et al. Among authors: scott d. Mol Cell Neurosci. 2019 Jul;98:32-45. doi: 10.1016/j.mcn.2019.04.001. Epub 2019 Apr 4. Mol Cell Neurosci. 2019. PMID: 30954537

10

Carbene footprinting accurately maps binding sites in protein-ligand and protein-protein interactions.

Manzi L, Barrow AS, Scott D, Layfield R, Wright TG, Moses JE, Oldham NJ. Manzi L, et al. Among authors: scott d. Nat Commun. 2016 Nov 16;7:13288. doi: 10.1038/ncomms13288. Nat Commun. 2016. PMID: 27848959 Free PMC article.

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