Scott CM - Search Results

1

SB-656104-A, a novel selective 5-HT7 receptor antagonist, modulates REM sleep in rats.

Thomas DR, Melotto S, Massagrande M, Gribble AD, Jeffrey P, Stevens AJ, Deeks NJ, Eddershaw PJ, Fenwick SH, Riley G, Stean T, Scott CM, Hill MJ, Middlemiss DN, Hagan JJ, Price GW, Forbes IT. Thomas DR, et al. Among authors: scott cm. Br J Pharmacol. 2003 Jun;139(4):705-14. doi: 10.1038/sj.bjp.0705290. Br J Pharmacol. 2003. PMID: 12812993 Free PMC article.

2

SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.

Scott C, Soffin EM, Hill M, Atkinson PJ, Langmead CJ, Wren PB, Faedo S, Gordon LJ, Price GW, Bromidge S, Johnson CN, Hagan JJ, Watson J. Scott C, et al. Eur J Pharmacol. 2006 Apr 24;536(1-2):54-61. doi: 10.1016/j.ejphar.2006.02.042. Epub 2006 Feb 28. Eur J Pharmacol. 2006. PMID: 16571351

3

Aripiprazole and its human metabolite are partial agonists at the human dopamine D2 receptor, but the rodent metabolite displays antagonist properties.

Wood MD, Scott C, Clarke K, Westaway J, Davies CH, Reavill C, Hill M, Rourke C, Newson M, Jones DN, Forbes IT, Gribble A. Wood MD, et al. Eur J Pharmacol. 2006 Sep 28;546(1-3):88-94. doi: 10.1016/j.ejphar.2006.07.008. Epub 2006 Jul 21. Eur J Pharmacol. 2006. PMID: 16925992

4

SB-236057, a selective 5-HT1B receptor inverse agonist, blocks the 5-HT human terminal autoreceptor.

Middlemiss DN, Göthert M, Schlicker E, Scott CM, Selkirk JV, Watson J, Gaster LM, Wyman P, Riley G, Price GW. Middlemiss DN, et al. Among authors: scott cm. Eur J Pharmacol. 1999 Jun 30;375(1-3):359-65. doi: 10.1016/s0014-2999(99)00262-9. Eur J Pharmacol. 1999. PMID: 10443589

5

SB-224289--a novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activity.

Selkirk JV, Scott C, Ho M, Burton MJ, Watson J, Gaster LM, Collin L, Jones BJ, Middlemiss DN, Price GW. Selkirk JV, et al. Br J Pharmacol. 1998 Sep;125(1):202-8. doi: 10.1038/sj.bjp.0702059. Br J Pharmacol. 1998. PMID: 9776361 Free PMC article.

6

5-HT(1A) receptor agonist-antagonist binding affinity difference as a measure of intrinsic activity in recombinant and native tissue systems.

Watson J, Collin L, Ho M, Riley G, Scott C, Selkirk JV, Price GW. Watson J, et al. Br J Pharmacol. 2000 Jul;130(5):1108-14. doi: 10.1038/sj.bjp.0703394. Br J Pharmacol. 2000. PMID: 10882396 Free PMC article.

7

SB-272183, a selective 5-HT(1A), 5-HT(1B) and 5-HT(1D) receptor antagonist in native tissue.

Watson J, Roberts C, Scott C, Kendall I, Collin L, Day NC, Harries MH, Soffin E, Davies CH, Randall AD, Heightman T, Gaster L, Wyman P, Parker C, Price GW, Middlemiss DN. Watson J, et al. Br J Pharmacol. 2001 Jul;133(6):797-806. doi: 10.1038/sj.bjp.0704133. Br J Pharmacol. 2001. PMID: 11454652 Free PMC article.

8

Characterisation of the binding of [3H]-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor.

Langmead CJ, Jerman JC, Brough SJ, Scott C, Porter RA, Herdon HJ. Langmead CJ, et al. Br J Pharmacol. 2004 Jan;141(2):340-6. doi: 10.1038/sj.bjp.0705610. Epub 2003 Dec 22. Br J Pharmacol. 2004. PMID: 14691055 Free PMC article.

9

SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'methyl-4'-(5-methyl-1,2,3-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): a novel, potent and selective 5-HT1B receptor antagonist.

Scott C, Langmead CJ, Clarke KL, Wyman P, Smith PW, Starr KR, Dawson LA, Price GW, Hagan JJ, Watson J. Scott C, et al. Neuropharmacology. 2006 Jun;50(8):984-90. doi: 10.1016/j.neuropharm.2006.01.008. Epub 2006 Mar 20. Neuropharmacology. 2006. PMID: 16546225

10

3,4-Dihydro-2H-benzoxazinones are 5-HT(1A) receptor antagonists with potent 5-HT reuptake inhibitory activity.

Atkinson PJ, Bromidge SM, Duxon MS, Gaster LM, Hadley MS, Hammond B, Johnson CN, Middlemiss DN, North SE, Price GW, Rami HK, Riley GJ, Scott CM, Shaw TE, Starr KR, Stemp G, Thewlis KM, Thomas DR, Thompson M, Vong AK, Watson JM. Atkinson PJ, et al. Among authors: scott cm. Bioorg Med Chem Lett. 2005 Feb 1;15(3):737-41. doi: 10.1016/j.bmcl.2004.11.030. Bioorg Med Chem Lett. 2005. PMID: 15664848

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