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Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in non-human primates.
Hermet P, Delache B, Herate C, Wolf E, Kivi G, Juronen E, Mumm K, Žusinaite E, Kainov D, Sankovski E, Virumäe K, Planken A, Merits A, Besaw JE, Yee AW, Morizumi T, Kim K, Kuo A, Berriche A, Dereuddre-Bosquet N, Sconosciuti Q, Naninck T, Relouzat F, Cavarelli M, Ustav M, Wilson D, Ernst OP, Männik A, LeGrand R, Ustav M Jr. Hermet P, et al. Among authors: sconosciuti q. PLoS Pathog. 2023 Aug 2;19(8):e1011532. doi: 10.1371/journal.ppat.1011532. eCollection 2023 Aug. PLoS Pathog. 2023. PMID: 37531329 Free PMC article.
Sotrovimab retains activity against SARS-CoV-2 omicron variant BQ.1.1 in a non-human primate model.
Hérate C, Marlin R, Touret F, Dereuddre-Bosquet N, Donati F, Relouzat F, Junges L, Galhaut M, Dehan O, Sconosciuti Q, Nougairède A, de Lamballerie X, van der Werf S, Le Grand R. Hérate C, et al. Among authors: sconosciuti q. Heliyon. 2023 Jun;9(6):e16664. doi: 10.1016/j.heliyon.2023.e16664. Epub 2023 May 30. Heliyon. 2023. PMID: 37287613 Free PMC article.
A Case Study to Dissect Immunity to SARS-CoV-2 in a Neonate Nonhuman Primate Model.
Fovet CM, Pimienta C, Galhaut M, Relouzat F, Nunez N, Cavarelli M, Sconosciuti Q, Dhooge N, Marzinotto I, Lampasona V, Tolazzi M, Scarlatti G, Ho Tsong Fang R, Naninck T, Dereuddre-Bosquet N, Van Wassenhove J, Gallouët AS, Maisonnasse P, Le Grand R, Menu E, Seddiki N. Fovet CM, et al. Among authors: sconosciuti q. Front Immunol. 2022 May 4;13:855230. doi: 10.3389/fimmu.2022.855230. eCollection 2022. Front Immunol. 2022. PMID: 35603150 Free PMC article.